Effectiveness of Cardiopulmonary Exercises for Children With Pectus Excavatum

NCT07300748 | Recruiting DMC

• 1 other identifier: AEŞH-EK-2025-168
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to investigate the effects of cardiopulmonary rehabilitation on respiratory function, exercise tolerance and posture in patients with pectus excavatum.

Conditions

Pectus Excavatum Deformity

Keywords

pectus excavatum; cardiopulmonary exercises

Outcome Measures

Primary Outcomes (1)

• Maximal inspiration and expiration pressure

  first day of exercises program and 5th week of exercises program

Secondary Outcomes (10)

• 6 minute walking test

  first day of exercises program and 5th week of exercises program

• New York Posture Scale

  first day of exercises program and 5th week of exercises program

• Measurement of chest expansion in centimetres using a tape measure

  first day of exercises program and 5th week of exercises program

• Assessment of symptoms (exercise intolerance, psychological impact, resting dyspnoea, chest pain, spinal pain, gastrointestinal symptoms, palpitations, dyspnoea) using a visual analogue scale

  first day of exercises program and 5th week of exercises program

• Cobb angle analysis using the Diers Formatrix 4D device (Wiesbaden, Germany)

  first day of exercises program and 5th week of exercises program

Study Arms (2)

cardiopulmonary exercises group at hospital

EXPERIMENTAL

The working group will be provided with a personalised exercise plan by a physiotherapist specialising in that field at the cardiopulmonary rehabilitation unit, to be carried out twice a week for five weeks. Patients will work on a bicycle ergometer. In addition, the same physiotherapist will demonstrate breathing and posture exercises for patients to perform at home.

Other: Cardiopulmonary exercises at hospital

pulmonary exercises group at home

ACTIVE COMPARATOR

The physiotherapist will only demonstrate the breathing and posture exercises that patients in the control group will perform at home.

Other: Pulmonary and posture exercises at home

Interventions

Pulmonary and posture exercises at home OTHER

The physiotherapist will demonstrate the breathing and posture exercises to be performed at home.

pulmonary exercises group at home

Cardiopulmonary exercises at hospital OTHER

Patients will exercise using a bicycle ergometer. In addition, the same physiotherapist will demonstrate breathing and posture exercises for them to perform at home.

cardiopulmonary exercises group at hospital

Eligibility Criteria

• Age: 5 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Children aged 5-18 years with pectus excavatum deformity
• Children undergoing conservative treatment (vacuum orthosis, exercise)
• Patients whose families have signed a consent form agreeing to participate in the study

You may not qualify if:

• Known cardiac disease
• Presence of an additional syndrome (Marfan syndrome, etc.)
• Cobb angle ≥10°
• Refusal to participate in the study
• Presence of mixed deformity (pectus arcuatum)
• Those with an indication for surgery

Sponsors & Collaborators

• Ankara Etlik City Hospital: lead

Study Sites (1)

Ankara Etlik City Hospital

Ankara, Yenimahalle, 06010, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Funnel Chest

Condition Hierarchy (Ancestors)

Bone Diseases, Developmental; Bone Diseases; Musculoskeletal Diseases; Musculoskeletal Abnormalities; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

Ayşe Naz Kalem Özgen, specialist

CONTACT

+90 0312 797 00 00; kalemnaz@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PM&R Specialist

Study Record Dates

• First Submitted: November 13, 2025
• First Posted: December 24, 2025
• Study Start: December 9, 2025
• Primary Completion (Estimated): May 9, 2026
• Study Completion (Estimated): May 9, 2026
• Last Updated: February 27, 2026

Record last verified: 2026-02

Locations

TU (1)