THE EFFECT OF ALVEOLAR RECRUITMENT MANOEUVRE ON INTRAOPERATIVE HAEMODYNAMICS

NCT07299396 | Completed

• 1 other identifier: BalikesirU OSagır 001
• Study Type: observational
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

Alveolar recruitment manoeuvre plays a key role in the prevention of atelectasis. In addition, it affects haemodynamic parameters. This study aims to investigate the effects of RM on haemodynamic parameters using minimally invasive monitoring techniques.

Conditions

Laparoscopic Hysterectomy; ASA Class I/II Patients Scheduled for Surgery Under General Anesthesia

Keywords

lung protective ventilation; recruitment manoeuvre; laparoscopic surgery; haemodynamic changes

Outcome Measures

Primary Outcomes (7)

• Effect of RM on heart rate (in bpm)

  measurement of heart rate in bpm

  perioperatively

• Effect of RM on pressure mmHg

  blood pressure measurement in mmmercury

  perioperatively

• Effect of RM on Cardiac index(CI)

  Cardiac Index measurement via an arterial cannula as l/min/m2

  intraoperatively

• Effect of RM on stroke volume index(SVI)

  SVI measurement via arterial cannula as L/min/m2

  intraoperatively

• Effect of RM on pulse pressure variablity(PPV)

  pulse pressure variability measured by finger probe as cm/s

  intraoperatively

• Effect of RM on systemic vascular resistance index(SVRI)

  systemic vascular resistance index(SVRI) measurement via arterial cannula as L/min/m2

  intraoperatively

• Effect of RM on cardiac power index(CPI)

  cardiac power index(CPI) measurement via arterial line as ml/min/m2

  intraoperatively

Secondary Outcomes (3)

• Effect of RM on Compliance

  intraoperatively

• Effect of RM on Oxygenation

  İntraoperatively

• Postoperative pulmonary comlications (infection, bronchospasm, pleural effusion, atelectasis, respiratory failure)

  postoperative day 1 and 3

Study Arms (2)

Alveolar Recruitment Maneuver Applied

Alveolar Recruitment Maneuver Not Applied

Eligibility Criteria

• Age: 18 Years - 70 Years
• Gender Eligibility Details: laparoscopic hysterectomy patients
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

* ASA I-II risk group patients * Patients between 18-70 y undergoing laparoscopic hysterectomy surgery

You may qualify if:

• ASA Class 1-2 patients 18-70 years old

You may not qualify if:

• \<18 y, BMI\>40
• Patients receiving invasive mechanical ventilator support in the last 1 month
• Patients who have received chemotherapy or radiotherapy in the last 2 months
• Those with severe lung disease (COPD, asthma, pulmonary infection, bronchiectasis, previous need for non-invasive mechanical ventilation, oxygen therapy or steroid therapy for acute attack)
• Known severe pulmonary hypertension
• Patient refusal to participate in the study
• Intracranial tumour
• Haemodynamic instability
• Shock
• Neuromuscular disease
• Pathologies causing increased intracranial and intraocular pressure
• Atrial fibrillation

Sponsors & Collaborators

• Balikesir University: lead

Study Sites (1)

Balikesir University

Balıkesir, 10145, Turkey (Türkiye)

Location

Study Officials

• Ahmet Koroglu, Professor, medical doctor

  Balikesir University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor, MD

Study Record Dates

• First Submitted: April 9, 2025
• First Posted: December 23, 2025
• Study Start: January 9, 2023
• Primary Completion: August 1, 2023
• Study Completion: August 15, 2023
• Last Updated: December 23, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will share

Locations

TU (1)