Mindfulness Psychoeducation for Bipolar Disorder

NCT07297056 | Completed

• 1 other identifier: OMER-RCT-2025-BAB
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled experimental study investigates the effectiveness of a mindfulness-based psychoeducation program on mindfulness, self-compassion, and forgiveness among individuals diagnosed with bipolar disorder. Bipolar disorder is a chronic psychiatric condition characterized by fluctuations in mood, energy, and functional capacity, often accompanied by emotional dysregulation, impaired insight, and challenges in interpersonal relationships. Psychosocial interventions that cultivate emotional awareness and adaptive coping may support recovery and enhance long-term functioning. In this study, 40 clinically stable patients with bipolar disorder were randomly assigned to either an experimental group (n=20) or a control group (n=20). The experimental group received a structured mindfulness-based psychoeducation program, while the control group received no additional intervention beyond usual care. Participants completed pre- and post-intervention assessments using a personal information form, the Mindfulness Scale, the Self-Compassion Scale-Short Form, and the Heartland Forgiveness Scale. Findings demonstrated that individuals who participated in the mindfulness-based psychoeducation program showed significantly greater improvements in mindfulness, self-compassion, and forgiveness compared with the control group. These results suggest that integrating mindfulness-based psychoeducation into routine care may promote emotional resilience, enhance illness insight, support symptom management, and strengthen interpersonal functioning in individuals with bipolar disorder.

Conditions

Mindfulness-Based Stress Reduction; Bipolar Disorder (BD); Mindfulness Meditation

Keywords

Bipolar disorder, forgiveness, mindfulness, psychiatric nursing, self-compassion.

Outcome Measures

Primary Outcomes (1)

• Change in Mindfulness Level (Mindful Attention Awareness Scale)

  Mindfulness level was assessed using the Mindful Attention Awareness Scale (MAAS), a self-report questionnaire consisting of 15 items. Total scores range from 15 to 90, with higher scores indicating greater levels of mindfulness. The outcome measure represents the change in total MAAS score from baseline to post-intervention.

  Baseline and 8 weeks

Secondary Outcomes (2)

• Between-group Differences in Post-intervention Mindfulness and Treatment Adherence Scores

  8 weeks

• Post-intervention Mindfulness and Treatment Adherence Scores Between Groups

  8 weeks

Study Arms (2)

Mindfulness-Based Psychoeducation

EXPERIMENTAL

Participants will receive an 8-session mindfulness-based psychoeducation program.

Other: Mindfulness-Based Psychoeducation Program; Other: routine care

Control: Routine Care

NO INTERVENTION

Participants in this arm will receive Routine Care provided by the psychiatric outpatient clinic. Routine Care includes standard follow-up, medication management, and usual clinical monitoring. No additional psychoeducation or mindfulness-based intervention will be provided during the study period.

Interventions

Mindfulness-Based Psychoeducation Program OTHER

A structured 8-session mindfulness-based psychoeducation program including mindfulness exercises, psychoeducation, breathing techniques and adherence-support strategies.

Mindfulness-Based Psychoeducation

routine care OTHER

Standard outpatient psychiatric care delivered by the clinic. No additional psychoeducation or mindfulness intervention is provided.

Mindfulness-Based Psychoeducation

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of bipolar disorder according to DSM-5 criteria
• Age between 18 and 65 years
• Clinically stable for at least the past 3 months
• Able to communicate, read, and understand Turkish
• Receiving outpatient psychiatric follow-up
• Willingness to participate and provide informed consent

You may not qualify if:

• Presence of acute psychotic symptoms requiring immediate hospitalization
• Comorbid intellectual disability, neurological disorder, or severe cognitive impairment
• Substance or alcohol dependence within the last 6 months
• Participation in any mindfulness-based or psychoeducational program within the last year
• Severe visual or hearing impairment preventing participation
• Any condition judged by the clinician to contraindicate participation in group sessions

Sponsors & Collaborators

• Ömer USLU: lead

Study Sites (1)

Söke Fehime Faik Kocagöz Hospital

Aydin, Söke, 09200, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Bipolar Disorder

Condition Hierarchy (Ancestors)

Bipolar and Related Disorders; Mood Disorders; Mental Disorders

Study Officials

• Ömer Uslu, PhD, RN

  Söke Fehime Faik Kocagöz Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Dr. Ömer Uslu, PhD - Principal Investigator

Model Details: Participants were randomly assigned to either the experimental group (mindfulness-based psychoeducation) or the control group with no intervention.

Study Record Dates

• First Submitted: December 9, 2025
• First Posted: December 22, 2025
• Study Start: March 3, 2025
• Primary Completion: May 2, 2025
• Study Completion: May 4, 2025
• Last Updated: December 31, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)