Expert Consensus on the Clinical Use of Skin Boosters: A Delphi-Based Recommendation Framework

NCT07296601 | Enrolling By Invitation

• 1 other identifier: Skin Booster-VenusRC
• Study Type: observational
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

This consensus research project aims to develop standardized, evidence-based recommendations for the clinical use of skin boosters in aesthetic dermatology. Despite their widespread adoption for improving skin hydration, texture, and dermal quality, current practice patterns vary significantly across clinicians and regions, with limited unified guidelines. Using a structured Delphi methodology, the study will gather expert opinions from dermatologists and aesthetic medicine specialists to achieve agreement on key aspects of skin booster therapy, including indications, patient selection, injection techniques, dosing protocols, product selection, treatment intervals, expected outcomes, and safety considerations. The project seeks to establish practical, consensus-driven guidelines that can harmonize clinical practice, enhance treatment outcomes, and ensure patient safety. The final recommendations will serve as a reference framework for practitioners and contribute to the standardization of skin quality enhancement treatments.

Conditions

Aesthetic Procedures; Cosmetic Techniques; Skin Ageing

Keywords

Skin booster; rejuvenation

Outcome Measures

Primary Outcomes (1)

• Degree of Consensus on Clinical Recommendations

  1. Degree of Consensus on Clinical Recommendations Definition: The level of expert agreement on each statement related to skin booster therapy. Measurement Method: Likert scale ratings (e.g., 1-9). Consensus threshold often defined as: ≥75% agreement within the 7-9 range (agreement) ≤15% ratings in the 1-3 range (disagreement) Outcome: Identification of statements that meet consensus criteria for inclusion in the final guideline. 2. Development of Final Consensus Guidelines Definition: The creation of a unified, evidence-informed set of recommendations on skin booster use. Measurement Method: Number of statements that reach consensus across all Delphi rounds. Completeness of guideline domains (indications, technique, dosing, safety, etc.). Outcome: A finalized recommendations document for clinicians.

  6-12 weeks

Secondary Outcomes (1)

• Implementation Readiness of Final Recommendations

  6-12 weeks

Study Arms (1)

Expert Panel

A cohort of dermatology and aesthetic medicine experts participating in a Modified Delphi process to develop consensus recommendations on skin booster use.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of a purposively selected panel of experts in aesthetic dermatology and skin booster therapy. Participants will include board-certified dermatologists, aesthetic physicians, and plastic surgeons with substantial clinical experience in administering injectable skin quality treatments. The expert panel will represent a diverse range of clinical backgrounds, geographical regions, and practice settings to ensure comprehensive and balanced perspectives.

You may qualify if:

• Experts will be eligible to participate if they meet all of the following:
• Board-certified dermatologist or aesthetic physician
• With recognized qualification in dermatology, aesthetic medicine, plastic surgery, or related fields.
• Minimum clinical experience
• At least 5 years of experience performing aesthetic injectable procedures.
• OR at least 3 years of consistent use of skin boosters in clinical practice.
• Demonstrated expertise in skin booster therapy
• Must have performed ≥100 skin booster procedures overall,
• OR ≥20 sessions per year over the past 2 years.
• Active clinical practice
• Currently practicing in an aesthetic or dermatology clinic, medical center, or hospital.
• Authorship or contribution to aesthetic/dermatology education (desirable but not mandatory)
• Publications, lectures, workshop instruction, or conference involvement in aesthetics.
• Ability to participate in Delphi rounds
• Must agree to complete all survey rounds within the specified timeframe.

You may not qualify if:

• Less than the required experience
• \<5 years of aesthetic practice
• OR insufficient hands-on experience with skin booster injections.
• Limited familiarity with skin booster products or techniques
• No regular use in the last 2 years.
• Has not performed the minimum number of required procedures.
• Industry conflict of interest
• Direct employment by a company manufacturing skin booster products.
• Significant financial relationship with a single product manufacturer that may bias responses.
• Inability to commit to multiple Delphi rounds
• Anticipated non-compliance or non-response in iterative rounds.
• Non-clinical or administrative professionals
• Those not actively practicing (e.g., retired, research-only positions, students, trainees).
• Participation in a competing guideline project
• Experts currently serving on another skin booster consensus panel to avoid duplication or bias.

Sponsors & Collaborators

• Venus Research Center: lead

Study Sites (1)

Venus Research Center

Cairo, Egypt

Location

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 8, 2025
• First Posted: December 22, 2025
• Study Start: December 25, 2025
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): January 1, 2027
• Last Updated: December 22, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)