Periodontal Status and Disease Severity in Hidradenitis Suppurativa Patients

NCT07294456 | Completed

• 1 other identifier: SUDE1824
• Study Type: observational
• Target: 226
• Locations: 1 country
• Sites: 1

Brief Summary

This cross-sectional study aims to evaluate the periodontal status of individuals diagnosed with hidradenitis suppurativa (HS) and to compare them with systemically healthy controls. HS is a chronic inflammatory skin disease characterized by recurrent lesions and systemic inflammation, which may influence periodontal health. In this study, periodontal parameters-including probing depth, clinical attachment loss, gingival index, plaque index, and bleeding on probing-will be assessed using standard clinical methods. Dermatological examination will include disease duration, lesion characteristics, and Hurley staging. The study will investigate the prevalence of periodontitis in HS patients and explore potential associations between periodontal findings and HS severity. Findings from this research may provide insight into shared inflammatory pathways and contribute to understanding the possible link between HS and periodontal disease.

Conditions

HİDRADENİTİS SUPPURATİVA

Keywords

HİDRADENİTİS SUPPURATİVA; PERİODONTAL DİSEASE; PERİODONTİTİS; GİNGİVAL İNFLAMMATİON

Outcome Measures

Primary Outcomes (1)

• Correlation Between Periodontal Status and Hidradenitis suppurativa

  Baseline (single assessment)

Secondary Outcomes (3)

• Correlation between Periodontal Status and Hurley Stage

  Baeline (single assesment)

• Corralation between Hurley Stage and Oral Health Impact Profile OHIP-14) Score

  baseline (single assesment)

• Correlation between Dermatology Life Quality Index (DLQI) and Oral Health Impact Profile (OHIP-14) Total Score

  baseline (single assesment)

Study Arms (2)

Hidradenitis Suppurativa Group

Participants diagnosed with hidradenitis suppurativa undergoing periodontal examination.

Other: No intervention (observational study)

Healthy Control Group

Systemically healthy individuals without hidradenitis suppurativa undergoing periodontal examination.

Other: No intervention (observational study)

Interventions

No intervention (observational study) OTHER

Observational study with no treatment or intervention applied.

Healthy Control Group; Hidradenitis Suppurativa Group

Eligibility Criteria

• Age: 18 Minutes+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of adult individuals with a confirmed diagnosis of hidradenitis suppurativa and age-matched healthy controls, each having at least 12 teeth (excluding third molars), and no recent periodontal or systemic treatment.

You may qualify if:

• Having a diagnosis of hidradenitis suppurativa.
• Age greater than 18 years.
• Presence of at least 12 teeth in the mouth, excluding third molars.

You may not qualify if:

• Age under 18 years.
• Pregnancy.
• Breastfeeding.
• Receiving treatment for periodontitis or hidradenitis suppurativa within the past 3 months.
• Use of antibiotics, anti-inflammatory drugs, or immunomodulatory medications within the past 3 months.

Sponsors & Collaborators

• Saglik Bilimleri Universitesi: lead

Study Sites (1)

University of Health Sciences, Gülhane Faculty of Dentistry

Ankara, None Selected, 6220, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Hidradenitis Suppurativa; Gingival Diseases; Dry Socket; Gingivitis

Interventions

Observation

Condition Hierarchy (Ancestors)

Skin Diseases, Bacterial; Bacterial Infections; Bacterial Infections and Mycoses; Infections; Skin Diseases, Infectious; Suppuration; Skin Diseases; Skin and Connective Tissue Diseases; Hidradenitis; Sweat Gland Diseases; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Methods; Investigative Techniques

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: ASSİSTANT PROFESSOR

Study Record Dates

• First Submitted: December 8, 2025
• First Posted: December 19, 2025
• Study Start: June 1, 2025
• Primary Completion: September 1, 2025
• Study Completion: September 15, 2025
• Last Updated: December 29, 2025

Record last verified: 2025-12

Locations

TU (1)