NCT07293104

Brief Summary

Pediatric patients differ in a variety of properties from adult populations, but comprehensive multicenter or population-based data is missing for pancreatic surgery. This study aimed to evaluate indications, complications, and mortality in pediatric pancreatic surgery.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
761

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2010

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
14 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

December 5, 2025

Completed
13 days until next milestone

First Posted

Study publicly available on registry

December 18, 2025

Completed
Last Updated

December 24, 2025

Status Verified

October 1, 2025

Enrollment Period

14 years

First QC Date

December 5, 2025

Last Update Submit

December 18, 2025

Conditions

Pancreatic SurgeryChildren

Keywords

ChidrenPancreatic surgerySurgical outcomes

Outcome Measures

Primary Outcomes (1)

  • Mortality rate

    Perioperative death

    30 days

Secondary Outcomes (1)

  • Complication rates

    30 days

Study Arms (5)

Pancreatic tumor

Procedure: PancreatoduodenectomyProcedure: Total pancreatectomyProcedure: Distal pancreatectomyProcedure: Anastomosis of the pancreatic ductProcedure: Incision of the pancreasProcedure: Internal drainage of the pancreasProcedure: Local excision destruction pancreasProcedure: Marsupialization of a pancreatic cystProcedure: Segmental pancreatic resection

Chronic pancreatitis

Procedure: PancreatoduodenectomyProcedure: Total pancreatectomyProcedure: Distal pancreatectomyProcedure: Anastomosis of the pancreatic ductProcedure: Incision of the pancreasProcedure: Internal drainage of the pancreasProcedure: Local excision destruction pancreasProcedure: Marsupialization of a pancreatic cystProcedure: Segmental pancreatic resection

Trauma

Procedure: PancreatoduodenectomyProcedure: Total pancreatectomyProcedure: Distal pancreatectomyProcedure: Anastomosis of the pancreatic ductProcedure: Incision of the pancreasProcedure: Internal drainage of the pancreasProcedure: Local excision destruction pancreasProcedure: Marsupialization of a pancreatic cystProcedure: Segmental pancreatic resection

Extra-pancreatic neoplasm

Procedure: PancreatoduodenectomyProcedure: Total pancreatectomyProcedure: Distal pancreatectomyProcedure: Anastomosis of the pancreatic ductProcedure: Incision of the pancreasProcedure: Internal drainage of the pancreasProcedure: Local excision destruction pancreasProcedure: Marsupialization of a pancreatic cystProcedure: Segmental pancreatic resection

Other diseases

Procedure: PancreatoduodenectomyProcedure: Total pancreatectomyProcedure: Distal pancreatectomyProcedure: Anastomosis of the pancreatic ductProcedure: Incision of the pancreasProcedure: Internal drainage of the pancreasProcedure: Local excision destruction pancreasProcedure: Marsupialization of a pancreatic cystProcedure: Segmental pancreatic resection

Interventions

PancreatoduodenectomyPROCEDURE

Procedure codes: 5-524.1; 5-524.2; 5-524.3

Chronic pancreatitisExtra-pancreatic neoplasmOther diseasesPancreatic tumorTrauma
Total pancreatectomyPROCEDURE

Procedure codes: 5-525.\*

Chronic pancreatitisExtra-pancreatic neoplasmOther diseasesPancreatic tumorTrauma
Distal pancreatectomyPROCEDURE

Procedure code: 5-524.0

Chronic pancreatitisExtra-pancreatic neoplasmOther diseasesPancreatic tumorTrauma
Anastomosis of the pancreatic ductPROCEDURE

Procedure codes: 5-527.\*

Chronic pancreatitisExtra-pancreatic neoplasmOther diseasesPancreatic tumorTrauma
Incision of the pancreasPROCEDURE

Procedure codes: 5-520.\*

Chronic pancreatitisExtra-pancreatic neoplasmOther diseasesPancreatic tumorTrauma
Internal drainage of the pancreasPROCEDURE

Procedure codes: 5-523.\*

Chronic pancreatitisExtra-pancreatic neoplasmOther diseasesPancreatic tumorTrauma
Local excision destruction pancreasPROCEDURE

Procedure codes: 5-521.\*

Chronic pancreatitisExtra-pancreatic neoplasmOther diseasesPancreatic tumorTrauma
Marsupialization of a pancreatic cystPROCEDURE

Procedure codes: 5-522.\*

Chronic pancreatitisExtra-pancreatic neoplasmOther diseasesPancreatic tumorTrauma
Segmental pancreatic resectionPROCEDURE

Procedure codes: 5-524.0\*; 5-524-x; 5-524.y

Chronic pancreatitisExtra-pancreatic neoplasmOther diseasesPancreatic tumorTrauma

Eligibility Criteria

AgeUp to 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

All persons addmitted to a German hospital between 2010 and 2023. Population-based dataset.

You may qualify if:

  • stationary hospital admission
  • pancreatic surgical procedure

You may not qualify if:

  • unknown sex or age
  • admission for pancreas tranplantation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Pancreaticoduodenectomy

Intervention Hierarchy (Ancestors)

Digestive System Surgical ProceduresSurgical Procedures, Operative

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

December 5, 2025

First Posted

December 18, 2025

Study Start

January 1, 2010

Primary Completion

December 31, 2023

Study Completion

December 31, 2023

Last Updated

December 24, 2025

Record last verified: 2025-10

Data Sharing

IPD Sharing
Will not share

The data is held and provided by the Federal Statistical Office of Germany and the statistical offices of the federal states. Due to data privacy regulations, data sharing is strictly prohibited by German law. Furthermore, the data was evaluated exclusively within the framework of controlled remote data analysis. This meant that we never had direct access to the raw data.