NCT07292558

Brief Summary

The goal of this study is to determine whether the Achieving Health in Emerging Adults with Diabetes (AHEAD) Program helps emerging adults with type 1 diabetes improve their blood glucose management during the transition from pediatric to adult care. Participants will be randomized to receive Usual Care or the AHEAD Program, which provides tailored support to emerging adults to build autonomy and competence to facilitate independent diabetes management. Researchers will compare changes in glycemia and participant-reported outcomes between groups.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
306

participants targeted

Target at P75+ for not_applicable

Timeline
31mo left

Started Dec 2025

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress13%
Dec 2025Dec 2028

First Submitted

Initial submission to the registry

November 24, 2025

Completed
21 days until next milestone

Study Start

First participant enrolled

December 15, 2025

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 18, 2025

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2028

Last Updated

December 30, 2025

Status Verified

December 1, 2025

Enrollment Period

3 years

First QC Date

November 24, 2025

Last Update Submit

December 28, 2025

Conditions

Keywords

AdolescentYoung adultEmerging adultPatient transferHealth care transitionTransition readinessDiabetes self-managementDiabetes distress

Outcome Measures

Primary Outcomes (1)

  • Hemoglobin A1c (HbA1c)

    HbA1c laboratory measurement.

    From enrollment (baseline clinic visit: 0 months) to the end of intervention period (6th clinic visit: 15-24 months).

Secondary Outcomes (11)

  • Time In Ranges

    From enrollment (baseline clinic visit: 0 months) to the end of intervention period (6th clinic visit: 15-24 months).

  • Diabetes Distress

    From enrollment (baseline clinic visit: 0 months) to the end of intervention period (6th clinic visit: 15-24 months).

  • Diabetes-Specific Health Care Transition Readiness

    From enrollment (baseline clinic visit: 0 months) to the end of intervention period (6th clinic visit: 15-24 months).

  • General Health Care Transition Readiness

    From enrollment (baseline clinic visit: 0 months) to the end of intervention period (6th clinic visit: 15-24 months).

  • Diabetes Family Conflict

    From enrollment (baseline clinic visit: 0 months) to the end of intervention period (6th clinic visit: 15-24 months).

  • +6 more secondary outcomes

Study Arms (2)

AHEAD Program

EXPERIMENTAL

AHEAD participants will receive support from a team of diabetes providers with expertise in supporting older adolescents and young adults who will work to build autonomy and competence needed to manage diabetes independently.

Behavioral: AHEAD Program

Usual Care

NO INTERVENTION

Usual Care participants will receive diabetes care as currently being provided by their primary medical team.

Interventions

AHEAD ProgramBEHAVIORAL

Participants will complete self-assessments around health care transition readiness and mental health prior to an AHEAD clinic visit. Emerging adults will then received tailored clinical support based on their self-assessments and work to build their autonomy and competence to manage their diabetes and health care independently with the support of their AHEAD providers.

AHEAD Program

Eligibility Criteria

Age16 Years - 19 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • years of age
  • Have had type 1 diabetes ≥ 12 months
  • Had a recent HbA1c ≥7.0%
  • Currently receive outpatient diabetes care at a Seattle Children's Hospital Diabetes Clinic located in Bellevue, Everett, Federal Way, or Seattle
  • Are able to complete written surveys
  • Will be able to receive clinical care in WA State for the next 2 years

You may not qualify if:

  • Have had a pilot program AHEAD clinic visit
  • Most recent Usual Care diabetes visit was with a current AHEAD provider

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seattle Children's

Seattle, Washington, 98101, United States

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Faisal S Malik, MD, MSc

    University of British Columbia

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Faisal S Malik, MD, MSc

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle Investigator

Study Record Dates

First Submitted

November 24, 2025

First Posted

December 18, 2025

Study Start

December 15, 2025

Primary Completion (Estimated)

December 1, 2028

Study Completion (Estimated)

December 1, 2028

Last Updated

December 30, 2025

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will share

The datasets generated during and/or analysed during the current study will be stored in a publicly available repository (OpenScience Framework: https://osf.io/). To address privacy and confidentiality concerns, sharing of data generated will be limited to de-identified data at the aggregate level.

Shared Documents
SAP
Time Frame
Data requests can be submitted at the end of the funding period and the data will be made accessible for up to 10 years.
Access Criteria
Access, distribution, and reuse of the data will require approval from study investigators.

Locations