Nutritional Effects of Supplementing Nonagenarians With a Supplement Based on a Fruit From the Cerrado: Buriti

NCT07289867 | Completed

• 1 other identifier: 6.790.431
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The population aged over 90 is growing worldwide, and the search for strategies to promote a better quality of life for the older persons is a challenge for science. Advancing age is associated with several physiological changes leading to different diseases, among which malnutrition and sarcopenia stand out. Malnutrition prevention and treatment are based on functional food/nutritional interventions, such as oral supplement use. However, studies evaluating the effectiveness of these supplements in nonagenarians are still scarce in the literature. The present study aimed to evaluate the use of a buriti fruit (Mauritia flexuosa) supplement in persons 90 years and older. The study included 40 individuals who were randomized into two groups. The group Supplement Test (ST) used a Buriti-based supplement with full vitamins and minerals; the control group used a capsule containing the same composition of vitamins and minerals as the test supplement, which was called Vitamin Mix (VM). The intervention lasted 12 weeks. The following analyses were carried out before and after this period: Mini Nutritional Assessment (MNA) questionnaire, handgrip strength (HGS), biochemical tests, and anthropometric measurements. The main results showed that the Buriti supplement led to a significant increase in body weight, Body Mass Index (BMI), handgrip strength, and globulins, when compared to the group that used the vitamin mix. Therefore, it can be concluded that the buriti supplement promotes an improvement in body composition, increased strength, and globulins in nonagenarians, and may be a viable and effective strategy for malnutrition treatment.

Conditions

Malnutrition in the Elderly

Keywords

Nonagenarians; malnutrition; Cerrado; nutritional supplements

Outcome Measures

Primary Outcomes (2)

• Change in Body Weight

  Body weight (kg) was measured using a calibrated digital scale to evaluate changes after supplementation.

  Baseline and after 12 weeks of supplementation

• Change in Muscle Strength

  Muscle strength was assessed using a handgrip dynamometer to evaluate functional improvement following 12 weeks of supplementation.

  Baseline and after 12 weeks of supplementation.

Secondary Outcomes (3)

• Change in Body Weight

  Baseline and after 12 weeks of supplementation

• Change in Body Mass Index

  Baseline and after 12 weeks of supplementation.

• Change in Serum Globulin Levels

  Baseline and after 12 weeks of supplementation.

Study Arms (2)

Supplement Group

EXPERIMENTAL

Participants received the supplement test (Nutricer Energia Zero-lactose) daily for 3 months

Dietary Supplement: Nutricer Energia Zero-lactose

Control Group (Multivitamin Mix)

ACTIVE COMPARATOR

Participants received a multivitamin mix daily for 3 months

Dietary Supplement: Multivitamin Mix

Interventions

Nutricer Energia Zero-lactose DIETARY_SUPPLEMENT

Daily administration of two tablespoons of solubilized in whole milk once a day for 3 months.

Also known as: Supplement Group

Supplement Group

Multivitamin Mix DIETARY_SUPPLEMENT

Daily administration of one multivitamin capsule for 3 months.

Also known as: Control Group (Multivitamin Mix)

Control Group (Multivitamin Mix)

Eligibility Criteria

• Age: 90 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Participants aged 90 or over were selected from the database of the Reference Center for Elderly Health Care in Montes Claros, MG .

Sponsors & Collaborators

• Federal University of Minas Gerais: lead

Study Sites (1)

State University of Minas Gerais

Montes Claros, Minas Gerais, Brazil

Location

MeSH Terms

Conditions

Malnutrition

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Nutrition Disorders; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Sérgio H Santos, PhD

  State University of Minas Gerais

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor / principal investigator

Model Details: This randomized clinical trial included 40 eligible participants, randomly assigned into two groups of 20. One group received a buriti-based supplement (Supplement Test - ST), while the control group received capsules containing the same vitamins and minerals (Vitamin Mix - VM). The intervention lasted 12 weeks, during which participants were evaluated before and after for nutritional status using the HAND test, anthropometric measurements, handgrip strength (HGS), and biochemical blood tests.

Study Record Dates

• First Submitted: December 4, 2025
• First Posted: December 17, 2025
• Study Start: May 1, 2024
• Primary Completion: August 26, 2024
• Study Completion: November 30, 2024
• Last Updated: December 17, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)