"Duration of Preoperative Clear Fluids Fasting in Patients Undergoing Liver Transplant"

NCT07288281 | Recruiting

• 1 other identifier: KB/67/2025
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this prospective observational study is to report the duration of preoperative clear fluids fasting in patients undergoing liver transplant. It will also learn about the relationship between the duration of preoperative clear fluids fasting and changes in hemodynamic variables and metabolic profile at various anesthesia and transplant phases. The main questions it aims to answer are:

• How long liver recipient fast from clear fluids before liver transplant?
• Is there any relationship between the duration of preoperative clear fluids fasting and changes in blood pressure and hear rate after the induction of anesthesia?
• Is there any relationship between the duration of preoperative clear fluids fasting and blood glucose concentration, blood lactate concentration and acid base balance during anesthesia for liver transplant?

Conditions

Liver Transplant Recipient; Preoperative Clear Fluid Fasting

Outcome Measures

Primary Outcomes (1)

• clear fluids fasting

  duration of preoperative clear fluids fasting in patients undergoing liver transplant

  before the induction of anesthesia

Other Outcomes (1)

• preoperative clear fluids fasting and changes in hemodynamic variables and metabolic profile

  after patient's coming to the operating room before induction of anesthesia till the end of the anhepatic phase of liver transplantation (just before the repercussion of liver graft)

Study Arms (1)

liver recipient

liver transplant recipient undergoing liver transplantation in University Clinical Center of Medical University of Warsaw

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with liver diseases scheduled for elective liver transplant at University Clinical Centre of Medical University of Warsaw

You may qualify if:

• patients scheduled for elective liver transplant

You may not qualify if:

• patients unable to give detailed answer on clear fluid fasting due to severe hepatic encephalopathy or cognitive impairment
• lack of written informed consent

Sponsors & Collaborators

• Medical University of Warsaw: lead

Study Sites (1)

University Clinical Centre of Medical University of Warsaw

Warsaw, Warszawa, 02-097, Poland

RECRUITING

Central Study Contacts

Paula Dudek, Medical Doctor

CONTACT

+49225992001; paula.dudek@wum.edu.pl

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 4, 2025
• First Posted: December 17, 2025
• Study Start: June 1, 2025
• Primary Completion: December 31, 2025
• Study Completion: February 1, 2026
• Last Updated: January 7, 2026

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

PL (1)