Evaluation of a Patient Decision Aid for Emergency Department Initiated Buprenorphine

NCT07278518 | Recruiting

• 1 other identifier: Pro00145434
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to develop and pilot test a patient decision aid (PtDA) for emergency department (ED)-initiated buprenorphine treatment for opioid use disorder (OUD). The PtDA will be evaluated for acceptability, impact on patient knowledge, decisional conflict, and buprenorphine uptake compared to treatment as usual (TAU).

Conditions

Opioid Use Disorder

Keywords

buprenorphine; patient decision aid; emergency department

Outcome Measures

Primary Outcomes (1)

• Acceptability of Intervention Measure (AIM)

  Day 1

Secondary Outcomes (4)

• Knowledge about MOUD

  pre and post intervention on day 1, and at 7 days

• Treatment selection

  Day 1

• Decisional Conflict Scale

  Day 1

• Receipt of buprenorphine

  Day 1, 7

Study Arms (2)

Patient Decision Aid

EXPERIMENTAL

This arm will receive the patient decision aid

Behavioral: Patient Decision Aid for Opioid Use Disorder

Treatment as Usual

NO INTERVENTION

This will be treatment as usual without the patient decision aid

Interventions

Patient Decision Aid for Opioid Use Disorder BEHAVIORAL

This will include information structured for patients about buprenorphine as a treatment options in the emergency department.

Patient Decision Aid

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥18
• DSM-5 criteria for moderate-to-severe OUD
• Speaks and reads English
• Not currently prescribed MOUD
• Post-ED discharge patients with access to video/email

You may not qualify if:

• \- Prisoners

Sponsors & Collaborators

• Medical University of South Carolina: lead
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

Medical University of South Carolina

Charleston, South Carolina, 29425, United States

RECRUITING

MeSH Terms

Conditions

Opioid-Related Disorders; Emergencies

Condition Hierarchy (Ancestors)

Narcotic-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Lindsey Jennings, MD, MPH

  Medical University of South Carolina

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Lindsey Jennings, MD, MPH

CONTACT

(843) 876-8023; jennil@musc.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor-Faculty

Study Record Dates

• First Submitted: December 3, 2025
• First Posted: December 12, 2025
• Study Start (Estimated): May 19, 2026
• Primary Completion (Estimated): October 30, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: March 11, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL

Locations

US (1)