NCT07277543

Brief Summary

Assessment of dentoskeletal changes after treatment of skeletal classII growing patient by twin block versus mono block ,clinical trial stuy

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 25, 2023

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 25, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 25, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 16, 2025

Completed
25 days until next milestone

First Posted

Study publicly available on registry

December 11, 2025

Completed
Last Updated

December 11, 2025

Status Verified

November 1, 2025

Enrollment Period

1.8 years

First QC Date

November 16, 2025

Last Update Submit

November 29, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • skeletal classII correction and dental changes

    standerized extraoral radiograph and Cone-Beam Computed Tomography(CBCT)

    8_12 month

Secondary Outcomes (1)

  • Assessment of airway changes

    8-12month

Study Arms (2)

treatment of skeletal classII by twin block

EXPERIMENTAL

growing patient wearing twin block appliance15 hrs/day

Device: wearing of twinblock after bite correction

treatment of skeletal classII by monoblock

EXPERIMENTAL

growing patients wearing monoblck appliance15hrs/day

Device: wearing of monoblock after bite correction

Interventions

bite registration at edge to edge position ,mono block wearing 15hrs/day

treatment of skeletal classII by monoblock

bite registration at edge to edge position ,twin block wearing 15hrs/day

treatment of skeletal classII by twin block

Eligibility Criteria

Age9 Years - 12 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Female patients to avoid any sexual dimorphism which may affect the comparison.
  • Skeletal Class II (ANB° \> 5°) with normal maxilla (SNA° = 82° ±4°) and retrognathic mandible (SNB° \< 87°).
  • Age range from 9 to 12 years.

You may not qualify if:

  • Previous history of orthodontic treatment.
  • Congenitally missing or extracted permanent teeth.
  • Posterior cross bites or severe maxillary transverse deficiency.
  • Severe facial asymmetry determined by clinical or radiographic examination.
  • Poor oral hygiene.
  • Systemic diseases that may affect the treatment results.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shimaa Nasr

Cairo, Egypt

Location

Related Publications (1)

  • Sakuno AC, da Rosa APB, Maeda FA, Trivino T, Carvalho PEG, Torres FC. Tomographic evaluation of dentoskeletal changes due to the treatment of class II malocclusion with Forsus appliance. J Oral Biol Craniofac Res. 2019 Jul-Sep;9(3):277-279. doi: 10.1016/j.jobcr.2019.06.005. Epub 2019 Jun 5.

Related Links

Study Officials

  • Maha Mostafa Mohammed, Ass.Professor

    Ass.Professor of Orthodontics

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principle investigator

Study Record Dates

First Submitted

November 16, 2025

First Posted

December 11, 2025

Study Start

October 25, 2023

Primary Completion

August 25, 2025

Study Completion

September 25, 2025

Last Updated

December 11, 2025

Record last verified: 2025-11

Data Sharing

IPD Sharing
Will not share

Locations