HopeMove App in Pediatric Cancer Patients

NCT07274358 | Completed

• 1 other identifier: KOCUN
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

This pilot feasibility study aims to assess the acceptability, usability, safety, and initial effects of the HopeMove mobile health app on fatigue in adolescents aged 13 to 18 years undergoing hematology-oncology treatment. HopeMove is a wearable-compatible app that offers guided home exercise sessions and daily symptom tracking to support physical activity and monitor well-being during treatment. The study includes an expert usability evaluation with 10 clinicians, a one-week usability testing phase with 15 adolescents, and an eight-week intervention period in which participants complete at least three exercise sessions per week using the app. Outcomes include usability measured with the Mobile Application Usability Scale, satisfaction assessed via a Visual Analog Scale, and fatigue evaluated with the Fatigue Scale. The findings are expected to provide evidence on the feasibility, usability, and potential clinical benefits of mobile-supported exercise programs for children and adolescents undergoing cancer treatment.

Conditions

Physical Activity; Mobile Application

Keywords

physical activity, fatigue, quality of life, mobile application

Outcome Measures

Primary Outcomes (2)

• Mobile Application Usability

  Mobile application usability was evaluated prior to the pilot study by a panel of experts in pediatric oncology, digital health, and user-centered design. Experts assessed the HopeMove application using a standardized usability assessment form that examined clarity of content, ease of navigation, appropriateness for the target age group, visual design, responsiveness, and overall user experience. Feedback from experts was used to refine and optimize the application before initiating the pilot trial.

  Prior to the initiation of the pilot trial (single assessment during the development phase)

• Fatigue

  Fatigue levels were assessed to evaluate the preliminary effectiveness of the HopeMove mobile application. Fatigue was measured using a standardized pediatric fatigue assessment tool administered before the intervention (at the initial meeting) and at the end of the 4-week feasibility period. Changes in fatigue scores were examined to explore whether engagement with the application was associated with improvements in perceived fatigue among participants.

  Baseline (initial meeting) and Week 4 (end of feasibility period)

Secondary Outcomes (1)

• Satisfaction for Mobile Application

  Week 4 (end of feasibility period)

Study Arms (1)

Intervention Group-HopeMove Application Group

EXPERIMENTAL

Participants assigned to the HopeMove Application Group will use HopeMove, a mobile application designed to promote and support physical activity among pediatric hematology and oncology patients. During the 4-week feasibility period, participants are instructed to engage with the application at least 3 days per week, completing the guided physical activity sessions provided within the app.

Other: HopeMove Mobile Application

Interventions

HopeMove Mobile Application OTHER

HopeMove is a mobile application developed to promote physical activity and support wellbeing among pediatric hematology-oncology patients. The application provides age-appropriate guided exercise sessions, motivational prompts, visual progress tracking, and individualized activity suggestions tailored to each participant's needs and abilities. During the feasibility study, participants were instructed to engage with the HopeMove application at least three days per week for a total duration of four weeks. Each session included structured physical activity modules designed to be safe and achievable during hospitalization or home recovery. The intervention focused on feasibility, usability, acceptability, and preliminary effects on outcomes such as fatigue and satisfaction. No masking was applied due to the nature of the digital intervention.

Intervention Group-HopeMove Application Group

Eligibility Criteria

• Age: 13 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• adolescents aged 13-18 years
• receiving active hematology-oncology treatment
• able to use a smartphone running Android operating system
• has internet access
• voluntarily agrees to participate
• parent/guardian consent obtained (if applicable)
• able to perform light-moderate exercise
• able to complete at least 75% of planned exercise sessions

You may not qualify if:

• having a chronic illness requiring regular invasive procedures,
• having received analgesics within the past 2 hours,
• having experienced a seizure within the past 2 hours,
• using antiepileptic medication,
• having a body temperature above 37.5°C
• not having parental consent,
• being agitated at the time of the procedure,
• having any auditory or visual impairments.

Sponsors & Collaborators

• Koç University: lead
• Istanbul University: collaborator

Study Sites (1)

Istanbul University

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Motor Activity; Fatigue

Condition Hierarchy (Ancestors)

Behavior; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Masking Details: Masking was not applied due to the nature of the intervention, and all participants and investigators were aware of the intervention being delivered.
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Teaching and Research Assistant

Model Details: Single-arm pilot feasibility study in which all participants receive the HopeMove intervention without a comparison group.

Study Record Dates

• First Submitted: November 27, 2025
• First Posted: December 10, 2025
• Study Start: August 1, 2025
• Primary Completion: November 15, 2025
• Study Completion: November 15, 2025
• Last Updated: December 10, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)