Nursing Needs of Patients With Cirrhosis

NCT07273331 | Enrolling By Invitation

• 1 other identifier: LSH-44-2025
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 2

Brief Summary

The primary objective of this study is to examine the quality of life, disease-related knowledge, and perceived nursing needs of adult patients diagnosed with liver cirrhosis who attend the outpatient clinic at Landspítali University Hospital. The study aims to generate clinically relevant insights that may inform improvements in nursing care and patient support. The research questions are: 1. what is the quality of life of patients with cirrhosis. 2. How do patients with cirrhosis describe their knowledge about the disease; and 3. How do patients with cirrhosis describe their nursing needs. Three questionnaires will be given to the patients. To assess quality of life Chronic Liver Disease Questionnaire (CLDQ) will be used. To validate knowledge and nursing needs two questionnaires will be used. The disease severity will be evaluated through clinical indicators such as MELD and Child-Pugh scores. In addition, the study will analyze demographic variables, including age, gender, education level, and employment status, to identify potential associations with quality of life, disease burden, and perceived care needs. By integrating clinical data, patient-reported outcomes, and sociodemographic factors, the study aims to support the development of evidence-based, individualized nursing strategies that enhance symptom management, reduce hospital admissions, and improve overall well-being for individuals living with liver cirrhosis in Iceland. The study has scientific value at national and international level, as it is based on a recognized measurement tool (CLDQ) and is in line with international emphasis on individualized treatment and early intervention in liver diseases. The results will provide deeper understanding of the quality of life and nursing needs of individuals with cirrhosis and support the development of targeted nursing services. The study can also shed light on the relationship between demographic factors and disease severity with service needs, as well as support policy development, education and improvements in the care of patients with chronic liver diseases. This study will have practical benefits for both patients and the Icelandic healthcare system. By identifying the specific nursing needs of individuals with cirrhosis, the study will support the development of targeted, individualized care plans that address symptom burden, disease progression, and psychosocial challenges. Improved nursing services, such as nutritional counseling, symptom management, and education about self-care of the disease, can improve patients' quality of life and promote greater independence.

Conditions

Cirrhoses, Liver

Keywords

cross-sectional study,; nursing

Outcome Measures

Primary Outcomes (1)

• Chronic Liver Disease Questionnaire score

  score will be collected

  November 2025 to End of August 2026

Study Arms (1)

patients with cirrhosis

patients with cirrhosis in outpatient clinic

Other: blood sample; Diagnostic Test: blood samples for analysis of cirrhosis

Interventions

blood sample OTHER

measurement of blood status related to cirrhosis

Also known as: interview

patients with cirrhosis

blood samples for analysis of cirrhosis DIAGNOSTIC_TEST

interviews and blood sample taken

patients with cirrhosis

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with cirrhosis in outpatient clinic at Landspitali

You may qualify if:

• Participants eligible for enrolment must meet the following criteria:
• Be 18 years of age or older
• Have a confirmed diagnosis of liver cirrhosis
• Be fluent in Icelandic or English, to ensure participants can comprehend study materials and provide informed consent.
• These criteria are designed to ensure that participants can meaningfully engage with the study procedures and provide reliable patient-reported data.

You may not qualify if:

• Exhibit severe cognitive impairment that may interfere with informed consent or the completion of questionnaires

Sponsors & Collaborators

• Landspitali University Hospital: lead
• University of Iceland: collaborator

Study Sites (2)

Eirberg Eiríksgata 34

Reykjavik, 105, Iceland

Location

Faculty of Nursing and Midwifery

Reykjavik, 105, Iceland

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

hemoglobin, platelets, white blood cell, ALP, AST, ALT, GGT, Bilirubin, Creatinine, Albumin, INR, Sodium, potassium, iron, iron binding capacity, ferritin, vitamin D, B-peth

MeSH Terms

Interventions

Blood Specimen Collection; Interviews as Topic

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques; Data Collection; Epidemiologic Methods; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: November 26, 2025
• First Posted: December 9, 2025
• Study Start: November 17, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): December 31, 2028
• Last Updated: December 9, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

IC (2)