NCT07270653

Brief Summary

Assesment of TMJ changes after treatment of skeletal classII growing patients by Twinblock vs Mono block applinces

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 15, 2023

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 11, 2025

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

November 19, 2025

Completed
19 days until next milestone

First Posted

Study publicly available on registry

December 8, 2025

Completed
Last Updated

December 8, 2025

Status Verified

November 1, 2025

Enrollment Period

2.1 years

First QC Date

November 19, 2025

Last Update Submit

November 26, 2025

Conditions

Skeletal Class II Malocclusion

Outcome Measures

Primary Outcomes (1)

  • Assessment of Tempromandibular changes including, condylar volume ( in cubic millimeters), length ( in millimeters) , height ( in millimeters) and position( in millimeters)

    full skull CBCT

    8-12 months

Study Arms (2)

Treatment of skeletal class II by mandibular advancement using Twin block appliance

EXPERIMENTAL

Twinblock group

Device: twin block

treatment of skeletal class II by mandibular advancement using Mono block appliance

EXPERIMENTAL

Monoblock group

Device: Mono block

Interventions

twin blockDEVICE

Treatment of Skeletal class II by mandibular advancement using twinblock appliances ( removable myofunctional appliance)

Treatment of skeletal class II by mandibular advancement using Twin block appliance
Mono blockDEVICE

Treatment of Skeletal class II by mandibular advancement using Mono block appliances ( removable myofunctional appliance)

treatment of skeletal class II by mandibular advancement using Mono block appliance

Eligibility Criteria

Age9 Years - 12 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • skeletal class II malocclusion
  • Defecient mandible
  • ANB \>4
  • Growing female patients
  • Age from 9-12 years

You may not qualify if:

  • TMJ disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Facility of dentistry, Alazhar university, girls branch

Cairo, Egypt

Location

Related Links

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

November 19, 2025

First Posted

December 8, 2025

Study Start

August 15, 2023

Primary Completion

September 30, 2025

Study Completion

November 11, 2025

Last Updated

December 8, 2025

Record last verified: 2025-11

Data Sharing

IPD Sharing
Will not share

Locations

EG(1)