Effects of Sarcopenia on Proprioception, Kinesiophobia, and Pressure Pain Threshold

NCT07269600 | Active Not Recruiting

• 1 other identifier: Beyza-ftr-01
• Study Type: observational
• Target: 31
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this observational study is to reveal the effect of sarcopenia on cervical proprioception, kinesiophobia and pressure pain threshold in geriatric individuals living in a nursing home. The main questions it aims to answer are as follows: The presence of sarcopenia in geriatric individuals living in a nursing home is effective/not effective on cervical proprioception. The presence of sarcopenia in geriatric individuals living in a nursing home is effective/not effective on kinesiophobia. The presence of sarcopenia in geriatric individuals living in a nursing home is effective/not effective on pressure pain threshold. As a result of the evaluations, we will obtain the answers to the above questions with the surveys and measurements conducted with the participants divided into two groups as control and sarcopenia groups.

Conditions

Sarcopenia in Elderly

Keywords

Pressure pain threshold; sarcopenia; crevical proprioception; kinesiophobia

Outcome Measures

Primary Outcomes (3)

• Assessment of cervical proprioception

  Cervical proprioception was assessed using joint position error test . While seated, the participant faced a board positioned 90 cm away at head level, consisting of concentric circles (40 cm diameter, 1-cm increments), and wore a cap with a mounted laser pointer The participant first aligned the laser with the central point to establish the neutral position, then-with eyes open-was guided through flexion, extension, right/left rotation, and right/left lateral flexion, returning to neutral after each movement. The same six movements were then actively performed with eyes closed . Six repetitions were completed for each direction, and the point at which the laser stopped was marked on the board after every trial . The mean of these points was calculated, and angular deviation from the target was determined using the arctan method based on the fixed distance to the board. A deviation of more than 4 degrees was considered to indicate impaired proprioception.

  0-8 months

• Assessment of kinesiophobia

  Kinesiophobia was assessed using the Kinesiophobia Causes Scale (KCS) . Developed by Kocjan and Knapik, the scale identifies the biological and psychological sources of fear of movement and contributes to understanding the underlying causes of reduced motor activity. It comprises two domains: biological and psychological. The biological domain includes morphological factors, movement requirements, energy resources, biological drives, negative experiences, motor competence, and beliefs related to body care, while the psychological domain assesses factors such as confidence, self-efficacy, and social interaction that contribute to avoidance behavior . The Turkish validity and reliability study was conducted by Çayır et al. The greater this value in the range of 0-5, the more valid the person's level of kinesiophobia.

  0-8 months

• Assessment of pressure pain threshold

  A pressure algometer (Baseline Force Gauge Model 12-0304; Baseline, NY, USA) will be used to assess the pressure pain threshold. The patient will be seated, and pressure will be applied perpendicularly and bilaterally using the algometer to different points in the cervical region (2 cm lateral to the C2 and C7spinous processes, at the midpoint of the upper part of the trapezius muscle) at a rate of approximately 3 N/s over an area of 0.5 cm² . The participant will be asked to report the moment they first felt discomfort and the pressure value at this moment will be recorded as the "pressure pain threshold". A second measurement will be taken at each region after an interval, the average of the two measurements will be noted.

  0-8months

Study Arms (2)

control group

individuals without sarcopenia

sarcopenic group

individuals with sarcopenia

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Geriatric people who lives in a nursing home in Ankara called Nevia Oran nursing home

You may qualify if:

• Being 65 years of age or older
• Receiving a score of 24 or higher, which is considered mentally healthy, according to the mini mental assessment
• Having at least 91 points or more according to the Barthel daily living activities index (being mildly dependent or completely independent)

You may not qualify if:

• Having a disability (such as limb, vision, hearing loss),
• Having a serious neurological, orthopedic or rheumatological disorder that may affect proprioception,
• Having uncontrolled hypertension/diabetes,
• Having pain in the spine and/or extremities,
• Having a psychiatric disease diagnosis.

Sponsors & Collaborators

• Atılım University: lead

Study Sites (1)

Nevia Oran Nursing Home

Ankara, çankaya, 06530, Turkey (Türkiye)

Location

Related Publications (45)

• Coşkun-Çelik, E., Medulla spinalis yaralanmalı hastalardaki nöropatik ağrıya akupunktur benzeri TENS'in etkisi. Uzmanlık Tezi, 2005.

  BACKGROUND

• Gürel, Ö., Değişik muskuloskeletal sistem hastalıklarının basınç ağrı eşiği üzerine etkisi. Uzmanlık Tezi, Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Fiziksel Tıp ve Rehabilitasyon Kliniği, İstanbul, 2009.

  BACKGROUND

• Mekanizmaları, E.S.A., Ağrı Sendromları ve Tedavisi 2. baskı. İstanbul: Gizben Matbaacılık, 2003: p. 33-42.261.

  BACKGROUND

• Düzel, V., Hemşire ve hastaların postoperatif ağrı değerlendirmelerinin karşılaştırılması. Çukurova Üniversitesi Sağlık Bilimleri Enstitüsü Yüksek Lisans Tezi. Adana, 2008.

  BACKGROUND

• Akyol, B., Üst ekstremite ve bel ağrı tanısı konulmuş sedanter kadınlarda kalistenik egzersizlerin ağrı eşiği üzerine etkisi. Yayımlanmamış doktora tezi), İnönü Üniversitesi, Malatya, 2014.

  BACKGROUND

• Wheeler CHB, Williams ACC, Morley SJ. Meta-analysis of the psychometric properties of the Pain Catastrophizing Scale and associations with participant characteristics. Pain. 2019 Sep;160(9):1946-1953. doi: 10.1097/j.pain.0000000000001494.

  PMID: 30694929 BACKGROUND

• Osman A, Barrios FX, Kopper BA, Hauptmann W, Jones J, O'Neill E. Factor structure, reliability, and validity of the Pain Catastrophizing Scale. J Behav Med. 1997 Dec;20(6):589-605. doi: 10.1023/a:1025570508954.

  PMID: 9429990 BACKGROUND

• Ugurlu, M., et al., Validity of Turkish form of Pain Catastrophizing Scale and modeling of the relationship between pain-related disability with pain intensity, cognitive, and emotional factors. Psychiatry and Clinical Psychopharmacology, 2017. 27(2): p. 189-196.

  BACKGROUND

• Sullivan, M.J., S.R. Bishop, and J. Pivik, The pain catastrophizing scale: development and validation. Psychological assessment, 1995. 7(4): p. 524.,

  BACKGROUND

• Kocjan, J. and A. Knapik, Barriers of physical activity (kinesiophobia) in patients subjected to cardiac rehabilitation. Baltic journal of health and physical activity, 2014. 6(4): p. 7.

  BACKGROUND

• Knapik A, Saulicz E, Gnat R. Kinesiophobia - introducing a new diagnostic tool. J Hum Kinet. 2011 Jun;28:25-31. doi: 10.2478/v10078-011-0019-8. Epub 2011 Jul 4.

  PMID: 23487514 BACKGROUND

• Çayır, M., N.A. Durutürk, and M.A. Tekindal, Kinezyofobi Nedenleri Ölçeği'nin Türkçe uyarlamasının geçerlik ve güvenirliği. Journal of Exercise Therapy and Rehabilitation, 2020. 7(1): p. 64-73.

  BACKGROUND

• GENÇ, F.Z. and N. BİLGİLİ, Huzurevinde Yaşayan Yaşlılarda Kinezyofobi ve İlişkili Faktörlerin Değerlendirilmesi. Balıkesir Sağlık Bilimleri Dergisi, 2023. 12(2): p. 294-303.

  BACKGROUND

• Benjaminse A, Sell TC, Abt JP, House AJ, Lephart SM. Reliability and precision of hip proprioception methods in healthy individuals. Clin J Sport Med. 2009 Nov;19(6):457-63. doi: 10.1097/JSM.0b013e3181bcb155.

  PMID: 19898072 BACKGROUND

• Ager AL, Borms D, Deschepper L, Dhooghe R, Dijkhuis J, Roy JS, Cools A. Proprioception: How is it affected by shoulder pain? A systematic review. J Hand Ther. 2020 Oct-Dec;33(4):507-516. doi: 10.1016/j.jht.2019.06.002. Epub 2019 Aug 31.

  PMID: 31481340 BACKGROUND

• Woollacott MH, Shumway-Cook A, Nashner LM. Aging and posture control: changes in sensory organization and muscular coordination. Int J Aging Hum Dev. 1986;23(2):97-114. doi: 10.2190/VXN3-N3RT-54JB-X16X.

  PMID: 3557634 BACKGROUND

• Ferlinc A, Fabiani E, Velnar T, Gradisnik L. The Importance and Role of Proprioception in the Elderly: a Short Review. Mater Sociomed. 2019 Sep;31(3):219-221. doi: 10.5455/msm.2019.31.219-221.

  PMID: 31762707 BACKGROUND

• Kristjansson E, Treleaven J. Sensorimotor function and dizziness in neck pain: implications for assessment and management. J Orthop Sports Phys Ther. 2009 May;39(5):364-77. doi: 10.2519/jospt.2009.2834.

  PMID: 19411769 BACKGROUND

• Bahat G, Tufan A, Kilic C, Karan MA, Cruz-Jentoft AJ. Prevalence of sarcopenia and its components in community-dwelling outpatient older adults and their relation with functionality. Aging Male. 2020 Dec;23(5):424-430. doi: 10.1080/13685538.2018.1511976. Epub 2018 Oct 5.

  PMID: 30290756 BACKGROUND

• Bahat G, Tufan A, Kilic C, Aydin T, Akpinar TS, Kose M, Erten N, Karan MA, Cruz-Jentoft AJ. Cut-off points for height, weight and body mass index adjusted bioimpedance analysis measurements of muscle mass with use of different threshold definitions. Aging Male. 2020 Dec;23(5):382-387. doi: 10.1080/13685538.2018.1499081. Epub 2018 Sep 29.

  PMID: 30269625 BACKGROUND

• Janssen I, Heymsfield SB, Baumgartner RN, Ross R. Estimation of skeletal muscle mass by bioelectrical impedance analysis. J Appl Physiol (1985). 2000 Aug;89(2):465-71. doi: 10.1152/jappl.2000.89.2.465.

  PMID: 10926627 BACKGROUND

• Ellis KJ, Bell SJ, Chertow GM, Chumlea WC, Knox TA, Kotler DP, Lukaski HC, Schoeller DA. Bioelectrical impedance methods in clinical research: a follow-up to the NIH Technology Assessment Conference. Nutrition. 1999 Nov-Dec;15(11-12):874-80. doi: 10.1016/s0899-9007(99)00147-1.

  PMID: 10575664 BACKGROUND

• Bahat G, Tufan A, Tufan F, Kilic C, Akpinar TS, Kose M, Erten N, Karan MA, Cruz-Jentoft AJ. Cut-off points to identify sarcopenia according to European Working Group on Sarcopenia in Older People (EWGSOP) definition. Clin Nutr. 2016 Dec;35(6):1557-1563. doi: 10.1016/j.clnu.2016.02.002. Epub 2016 Feb 11.

  PMID: 26922142 BACKGROUND

• Dodds R, Sayer AA. Sarcopenia. Arq Bras Endocrinol Metabol. 2014 Jul;58(5):464-9. doi: 10.1590/0004-273000000.

  PMID: 25166036 BACKGROUND

• Testa G, Vescio A, Zuccala D, Petrantoni V, Amico M, Russo GI, Sessa G, Pavone V. Diagnosis, Treatment and Prevention of Sarcopenia in Hip Fractured Patients: Where We Are and Where We Are Going: A Systematic Review. J Clin Med. 2020 Sep 17;9(9):2997. doi: 10.3390/jcm9092997.

  PMID: 32957453 BACKGROUND

• Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyere O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, Schneider SM, Sieber CC, Topinkova E, Vandewoude M, Visser M, Zamboni M; Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019 Jan 1;48(1):16-31. doi: 10.1093/ageing/afy169.

  PMID: 30312372 BACKGROUND

• Yee XS, Ng YS, Allen JC, Latib A, Tay EL, Abu Bakar HM, Ho CYJ, Koh WCC, Kwek HHT, Tay L. Performance on sit-to-stand tests in relation to measures of functional fitness and sarcopenia diagnosis in community-dwelling older adults. Eur Rev Aging Phys Act. 2021 Jan 8;18(1):1. doi: 10.1186/s11556-020-00255-5.

  PMID: 33419399 BACKGROUND

• Yoshiko A, Ogawa M, Shimizu K, Radaelli R, Neske R, Maeda H, Maeda K, Teodoro J, Tanaka N, Pinto RS, Akima H. Chair sit-to-stand performance is associated with diagnostic features of sarcopenia in older men and women. Arch Gerontol Geriatr. 2021 Sep-Oct;96:104463. doi: 10.1016/j.archger.2021.104463. Epub 2021 Jun 14.

  PMID: 34218157 BACKGROUND

• HALİL, M., Z. ÜLGER, and S. ARIOĞLU, Sarkopeniye yaklaşım. Hacettepe Tıp Dergisi. 42. S: 123-132. 2011.

  BACKGROUND

• Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, Abellan van Kan G, Andrieu S, Bauer J, Breuille D, Cederholm T, Chandler J, De Meynard C, Donini L, Harris T, Kannt A, Keime Guibert F, Onder G, Papanicolaou D, Rolland Y, Rooks D, Sieber C, Souhami E, Verlaan S, Zamboni M. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc. 2011 May;12(4):249-56. doi: 10.1016/j.jamda.2011.01.003. Epub 2011 Mar 4.

  PMID: 21527165 BACKGROUND

• Cruz-Jentoft AJ, Sayer AA. Sarcopenia. Lancet. 2019 Jun 29;393(10191):2636-2646. doi: 10.1016/S0140-6736(19)31138-9. Epub 2019 Jun 3.

  PMID: 31171417 BACKGROUND

• Telli, H. and Ç. Özdemir, The Effects of Sarcopenia and Fracture Risk on Kinesiophobia, Fear of Falling, Fall Risk and Quality of Life in Geriatric Individuals. Turk J Osteoporos, 2024. 30(2): p. 75-88.

  BACKGROUND

• Kulkarni V, Chandy MJ, Babu KS. Quantitative study of muscle spindles in suboccipital muscles of human foetuses. Neurol India. 2001 Dec;49(4):355-9.

  PMID: 11799407 BACKGROUND

• Humphreys BK. Cervical outcome measures: testing for postural stability and balance. J Manipulative Physiol Ther. 2008 Sep;31(7):540-6. doi: 10.1016/j.jmpt.2008.08.007.

  PMID: 18804005 BACKGROUND

• Ribeiro, F. and J. Oliveira, Aging effects on joint proprioception: the role of physical activity in proprioception preservation. European review of aging and physical activity, 2007. 4(2): p. 71-76.

  BACKGROUND

• Cawthon PM, Lui LY, Taylor BC, McCulloch CE, Cauley JA, Lapidus J, Orwoll E, Ensrud KE. Clinical Definitions of Sarcopenia and Risk of Hospitalization in Community-Dwelling Older Men: The Osteoporotic Fractures in Men Study. J Gerontol A Biol Sci Med Sci. 2017 Oct 1;72(10):1383-1389. doi: 10.1093/gerona/glw327.

  PMID: 28329087 BACKGROUND

• Steffl M, Bohannon RW, Sontakova L, Tufano JJ, Shiells K, Holmerova I. Relationship between sarcopenia and physical activity in older people: a systematic review and meta-analysis. Clin Interv Aging. 2017 May 17;12:835-845. doi: 10.2147/CIA.S132940. eCollection 2017.

  PMID: 28553092 BACKGROUND

• Schaap LA, van Schoor NM, Lips P, Visser M. Associations of Sarcopenia Definitions, and Their Components, With the Incidence of Recurrent Falling and Fractures: The Longitudinal Aging Study Amsterdam. J Gerontol A Biol Sci Med Sci. 2018 Aug 10;73(9):1199-1204. doi: 10.1093/gerona/glx245.

  PMID: 29300839 BACKGROUND

• Dos Santos L, Cyrino ES, Antunes M, Santos DA, Sardinha LB. Sarcopenia and physical independence in older adults: the independent and synergic role of muscle mass and muscle function. J Cachexia Sarcopenia Muscle. 2017 Apr;8(2):245-250. doi: 10.1002/jcsm.12160. Epub 2016 Nov 8.

  PMID: 27897417 BACKGROUND

• Bischoff-Ferrari HA, Orav JE, Kanis JA, Rizzoli R, Schlogl M, Staehelin HB, Willett WC, Dawson-Hughes B. Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older. Osteoporos Int. 2015 Dec;26(12):2793-802. doi: 10.1007/s00198-015-3194-y. Epub 2015 Jun 12.

  PMID: 26068298 BACKGROUND

• Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinkova E, Vandewoude M, Zamboni M; European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010 Jul;39(4):412-23. doi: 10.1093/ageing/afq034. Epub 2010 Apr 13.

  PMID: 20392703 BACKGROUND

• Derya, K., et al., Geriatri poliklinik olgularında geriatrik sendromlar: 1048 olgunun analizi. Ege Tıp Dergisi, 2018. 57(1): p. 31-35.

  BACKGROUND

• Carlson C, Merel SE, Yukawa M. Geriatric syndromes and geriatric assessment for the generalist. Med Clin North Am. 2015 Mar;99(2):263-79. doi: 10.1016/j.mcna.2014.11.003. Epub 2015 Jan 10.

  PMID: 25700583 BACKGROUND

• Buz, S., Yaşlı bireylere yönelik yaş ayrımcılığı. Elektronik Sosyal Bilimler Dergisi, 2015. 14(53).

  BACKGROUND

• Beğer, T. and H. Yavuzer, Yaşlılık ve yaşlılık epidemiyolojisi. Klinik gelişim, 2012. 25(3): p. 1-3.

  BACKGROUND

Related Links

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MeSH Terms

Conditions

Sarcopenia; Kinesiophobia

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Phobic Disorders; Anxiety Disorders; Mental Disorders

Study Officials

• nagihan acet, assistant professor

  atılım üniversity

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 2 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: pyhsiotherapist

Study Record Dates

• First Submitted: November 14, 2024
• First Posted: December 8, 2025
• Study Start: April 1, 2025
• Primary Completion: December 31, 2025
• Study Completion: January 30, 2026
• Last Updated: December 15, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: CSR

Locations

TU (1)