Clinical and Radiographic Evaluation of Implants in Protective Occlusion

NCT07256379 | Completed DMC

• 1 other identifier: IDCE-16112025
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

Occlusal overload may lead to a number of complications; biological and mechanical such as crestal bone loss, screw loosening, prosthetic fracture and even implant failure . Inadequate occlusal scheme (occlusion) causes occlusal overload increasing mechanical stresses which are transferred to the crestal bone and implant interface, leading to complications such as; Early implant failure, Early crestal bone loss, Intermediate to late implant failure, Intermediate to late implant bone loss, Screw loosening (abutment and prosthesis coping), Uncemented restoration, Component fracture, Porcelain fracture, Prosthesis fracture and Peri implant disease .Thus, a proper implant occlusal scheme plays a major role in the outcome of the implant treatment modality.

Conditions

Implant Occlusion

Keywords

Implant Occlusion, protective occlusion

Outcome Measures

Primary Outcomes (2)

• Marginal Bone Loss

  • To evaluate marginal bone loss using bitewing radiographs in mm.

  2 years

• Stability

  • to assess implant micromotion in both groups by resonance frequency analysis (Osstell®) in mm.

  2 years

Study Arms (2)

Protective occlusion

ACTIVE COMPARATOR

According to the literature, Misch introduced the concept of implant-protective occlusion (IPO) (Misch and Bidez, 1994) based on basic prosthetic concepts, bone biomechanical principles and finite element analysis, which refers to an occlusal scheme designed for implant restoration, promoting the conditions for less biomechanical complications by reducing the stress to the implant interface and enhancing the longevity of the implant and prosthesis. It mainly entails the elimination of premature occlusal contacts or interferences.

Procedure: Protective occlusion

Maximum Intercuspation

EXPERIMENTAL

Procedure: Maximum Intercusption

Interventions

Maximum Intercusption PROCEDURE

to evaluate crestal bone loss, chewing efficiency and prosthetic complications after single posterior implant restoration in protective occlusion in comparison to maximum intercuspation occlusion.

Maximum Intercuspation

Protective occlusion PROCEDURE

To evaluate crestal bone loss, chewing efficiency and prosthetic complications after single posterior implant restoration in protective occlusion in comparison to maximum intercuspation occlusion.

Protective occlusion

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients who have a single posterior (1st or second molar) bounded implant with opposing natural tooth teeth.
• Adults above the age of 18.
• Good oral hygiene.
• Patient accepts to provide informed consent.

You may not qualify if:

• Smokers.
• Pregnant and lactating females.
• Medically compromised patients.
• Patients with untreated active periodontal diseases.
• Patients with parafunctional habits.

Sponsors & Collaborators

• International Dental Contiuing Education: lead

Study Sites (1)

International Dental Continuing Education

Cairo, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: NETWORK
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 20, 2025
• First Posted: December 1, 2025
• Study Start: September 1, 2022
• Primary Completion: May 1, 2025
• Study Completion: May 1, 2025
• Last Updated: December 22, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)