EFFECT OF EARLY WEIGHT BEARING AND ACTIVE KNEE EXERCISES IN TREATMENT OF TIBIAL PLATEAU FRACTURES

NCT07251699 | Enrolling By Invitation DMC

• 1 other identifier: tibial plateau early rehab
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

This study will answer the following research questions: Are there any significant differences between combination of early active knee ROM exercises and weight bearing versus early passive ROM with delayed weight bearing on pain intensity, ROM knee flexion and extension, function, and radiological healing in treatment of patients with TPFs fixed with plates and screws?

Conditions

Tibial Plateau Fractures

Keywords

early reabilitation

Outcome Measures

Primary Outcomes (2)

• Numerical Pain Rating Scale

  This scale will be used to measure pain intensity. It is a valid and reliable scale for pain intensity measurement, (

  5 min

• Modified Rasmussen Radiologic Score

  This chart is valid measurement tool for assessing fracture healing

  5 min

Secondary Outcomes (2)

• Universal Goniometer

  5 min

• Arabic version of the Knee injury and Osteoarthritis Outcome Score (KOOS)

  5 min

Study Arms (2)

Group A will receive early active knee ROM exercises with weight 24 bearing.

EXPERIMENTAL

Group A Early active exercises will be applied from the first day by the participation of the patient with the assistance of the physiotherapist as follows: Weeks: 1-4 The program will be applied according to (Mohamed et al., 2022) as follows: Week: 1 Day: 1-2: 1. Static quadriceps, hamstrings and glutei. 2. Static abdominal and back exercises. 3. Active knee flexion and extension ROM exercises as possible according to patient tolerance and pain. Day: 3-4: In addition to the previous we add the following 1. Ankle toe movement. 2. Active exercises of the unaffected limb. 3. Respiratory exercises. 33 4. Cryotherapy. 5. Active assisted hip abduction (0° -10°). 6. Ankle toe movement; heel slides (0°-5°). Day: 5-7 In addition to previous exercises, the following exercises will be added: 1. Half bridging exercise. 2. Active SLR (0°-15°). 3. Active abduction (0°-15°). 4. Active adduction (15°-0°). 5. Heel slides (0°-10°). Weight bering excecises Ten percent of load on the affect leg

Other: Early active exercises will be applied from the first day by the participation of the patient with the assistance of the physiotherapist

Group B will receive early passive ROM with delayed weight bearing.

ACTIVE COMPARATOR

Passive ROM will be applied from the first day according to (Arslan, A et al., 2015) and late weight bearing based on (Amin et al.,2023) as follows: Weeks: 1-4 1. Cryotherapy for 10 minutes three times per day. 2. Passive exercises: 1. ROM exercises. 2. Passive ankle toe movements for 10 repetitions. 3. Passive knee flexion as tolerated The program will be applied without active participation from the patient. It will be applied by the physiotherapist. 3. Weight bearing is mainly in the sound side not affected so no weight bearing in the affected limb for about four weeks (Amin et al., 2023). Weeks: 5-8 Same protocol as Group A. Weeks: 9-12 Same protocol as Group A. Weeks: 13-16 Same protocol as Group A. The difference between each group is in the first four weeks and the type of program group one started with active exercise from the first day 38 group 2 active exercises started from week five at the first four weeks program is done by passive ROM modalities and by the physiotherapis

Other: Early active exercises will be applied from the first day by the participation of the patient with the assistance of the physiotherapist

Interventions

Early active exercises will be applied from the first day by the participation of the patient with the assistance of the physiotherapist OTHER

The difference between each group is in the first four weeks and the type of program group one started with active exercise from the first day 38 group 2 active exercises started from week five at the first four weeks program is done by passive ROM modalities and by the physiotherapist. Early weight bearing is early in group 1 from the first week and late in group 2 after four weeks

Group A will receive early active knee ROM exercises with weight 24 bearing.; Group B will receive early passive ROM with delayed weight bearing.

Eligibility Criteria

• Age: 25 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

faculty of physical therapy cairo university, Giza,

Giza, Giza Governorate, Egypt

Location

MeSH Terms

Conditions

Tibial Plateau Fractures

Condition Hierarchy (Ancestors)

Knee Fractures; Fractures, Bone; Wounds and Injuries; Tibial Fractures; Knee Injuries; Leg Injuries

Study Officials

• enas fawzy mohamed, phd

  Enas.fawzy@pt.cu.edu.eg

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
• Masking Details: A triple-blinded clinical randomized trial: (the research assistant, the participants, and the statistician) will be blinded to the treatment groups.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: phyisical therapist at qena oncology center

Model Details: A triple-blinded clinical randomized trial: (the research assistant, the participants, and the statistician) will be blinded to the treatment groups.

Study Record Dates

• First Submitted: November 19, 2025
• First Posted: November 26, 2025
• Study Start: November 1, 2024
• Primary Completion (Estimated): November 1, 2026
• Study Completion (Estimated): November 1, 2026
• Last Updated: November 26, 2025

Record last verified: 2025-11

Locations

EG (1)