Rehabilitation Exercise Intervention for Rheumatoid Arthritis Patients Using Artificial Intelligence-Based Exercise Prescription System
1 other identifier
interventional
147
1 country
1
Brief Summary
This is a single-center, randomized, parallel-controlled trial evaluating the efficacy and safety of an artificial intelligence-based exercise prescription system for rehabilitation in rheumatoid arthritis (RA) patients. A total of 147 patients with low-to-moderate disease activity will be randomly assigned to three groups: AI exercise prescription group (personalized AI system guidance), paper exercise prescription group (traditional paper guidance), and routine care group. The intervention will last for 6 weeks with 6-month follow-up assessments evaluating joint function, pain, and quality of life indicators.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Nov 2025
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 11, 2025
CompletedFirst Posted
Study publicly available on registry
November 24, 2025
CompletedStudy Start
First participant enrolled
November 30, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 15, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
March 15, 2026
CompletedNovember 24, 2025
August 1, 2025
15 days
August 11, 2025
November 20, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Knee flexion range of motion
Knee Flexion Range of Motion Unit of Measure: Degrees (°) Knee flexion range of motion refers to the maximum angle through which the knee joint can bend, measured from the straight (extended) position to the farthest point the lower leg can move toward the thigh. This assessment evaluates the flexibility and functional mobility of the knee, which is critical for daily activities such as walking, climbing stairs, and sitting. Relevant definitions and criteria: A "normal" range of motion for knee flexion in adults is generally considered to be 135° to 150°, though this can vary slightly based on age, physical conditioning, and individual anatomy. Limited knee flexion (e.g., less than 90°) may indicate joint stiffness, muscle tightness, or underlying issues such as injury, arthritis, or post-surgical scarring.
Baseline, post-intervention (6 weeks), 3-month follow-up, 6-month follow-up
Secondary Outcomes (12)
Hospital for Special Surgery (HSS) Score
Baseline, post-intervention (6 weeks), 3-month follow-up, 6-month follow-up
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
Baseline, post-intervention (6 weeks), 3-month follow-up, 6-month follow-up
Timed Up and Go (TUG) Test
Baseline, post-intervention (6 weeks), 3-month follow-up, 6-month follow-up
Berg Balance Scale (BBS)
Baseline, post-intervention (6 weeks), 3-month follow-up, 6-month follow-up
Isokinetic Muscle Strength Test
Baseline, post-intervention (6 weeks), 3-month follow-up, 6-month follow-up
- +7 more secondary outcomes
Study Arms (3)
Routine Care Group
ACTIVE COMPARATORReceives standardized RA disease management education and basic joint mobility exercises provided by rheumatology nurses.
Paper Exercise Prescription Group
ACTIVE COMPARATORReceives paper-based exercise prescription developed by rehabilitation therapists, including warm-up, formal training (bridging, modified bird-dog exercise, etc.) and cool-down stretching.
AI Exercise Prescription Group
EXPERIMENTALUses "Yidong Health AI Exercise Prescription System" delivered via WeChat mini-program, providing personalized exercise prescriptions (three sets: A/B/C) with AI Q\&A module. Physicians adjust prescriptions weekly based on patient feedback.
Interventions
Uses "Yidong Health AI Exercise Prescription System" delivered via WeChat mini-program, providing personalized exercise prescriptions (three sets: A/B/C) with AI Q\&A module. Physicians adjust prescriptions weekly based on patient feedback.
Receives standardized RA disease management education and basic joint mobility exercises provided by rheumatology nurses.
Receives paper-based exercise prescription developed by rehabilitation therapists, including warm-up, formal training (bridging, modified bird-dog exercise, etc.) and cool-down stretching.
Eligibility Criteria
You may qualify if:
- Age ≥18 years Meets 2010 ACR/EULAR classification criteria for RA Low-to-moderate disease activity (assessed by rheumatologist) Knee joint involvement Willing and able to provide informed consent
You may not qualify if:
- Existing joint ankylosis (fibrous or bony) Acute flare or extra-articular soft tissue lesions Comorbid with other rheumatic diseases (e.g., SLE, Sjögren's syndrome) Severe hepatic or renal impairment Knee joint VAS pain score \>4 (0-10 scale) Psychiatric disorders
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Rehabilitation Medicine, Peking University People's Hospital
Beijing, Beijing Municipality, 100000, China
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 11, 2025
First Posted
November 24, 2025
Study Start
November 30, 2025
Primary Completion
December 15, 2025
Study Completion
March 15, 2026
Last Updated
November 24, 2025
Record last verified: 2025-08