Conventional Physical Therapy Action Observation Therapy on Freezing of Gait and Functional Mobility in Parkinson's Disease

NCT07244900 | Completed DMC

• 1 other identifier: Kiran Maqsood
• Study Type: interventional
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this study is to determine the effects of action observation therapy with conventional physical therapy on freezing gait and functional limitation in participants with Parkinson's disease.

Conditions

Parkinson Disease; Neuro-Degenerative Disease

Keywords

Parkinson's Disease; Balance; Freezing of Gait; Mobility; Function

Outcome Measures

Primary Outcomes (2)

• Change in functional mobility

  The TUG is an efficient test that measures mobility and balance, requiring participants to rise from a chair, walk 3 meters, turn, walk back, and sit down. The time taken to complete this sequence is recorded, with longer times indicating potential mobility issues. A score of more than or equal to fourteen seconds indicates a high risk of falls.

  The assessment was made at baseline before the treatment session, and any change in mobility status was observed at the end of 6th week and 12th week after the intervention.

• Change in Freezing of gait

  The FOG-Q is a reliable tool for evaluating the effectiveness of treatment intervention on FOG for Parkinson's disease. The questionnaire consists of 6 items designed to assess the severity of freezing of gait. Each item is rated on a five-point Likert scale, with '0' indicating no symptoms and '4' indicating the most severe symptoms. The total score can range from 0 to 24, with higher scores indicating greater severity of freezing of gait.

  The freezing of gait was assessed at baseline, and any change in it was measured at the end of 6th week and 12th week after the intervention.

Study Arms (2)

Conventional Physiotherapy Group

ACTIVE COMPARATOR

This group included conventional physical therapy that contains isometric exercise, stretching techniques, and strength and balance training.

Other: Conventional Physical Therapy

Experimental Group

EXPERIMENTAL

This group included action observation therapy in addition to conventional physical therapy, in which small videos containing specific task will be made available to follow to the participants.

Other: Action Observation plus conventional Physical Therapy

Interventions

Conventional Physical Therapy OTHER

Group A received conventional physical therapy treatment. The CPT program consists of isometric exercises, stretching, and strength training based on the patient's physical condition and the severity of functional mobility and freezing of Gait.

Conventional Physiotherapy Group

Action Observation plus conventional Physical Therapy OTHER

Group B was given action observation therapy with conventional physical therapy treatment. In AOT, the therapist showed small video clips of different goal-directed tasks to participants, and they were asked to follow every step and movement. The therapist maintained the patient's attention with verbal feedback

Experimental Group

Eligibility Criteria

• Age: 50 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

Sponsors & Collaborators

• University of Lahore: lead

Study Sites (1)

The University of Lahore

Lahore, Punjab Province, 54000, Pakistan

Location

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Ishfaq Ahmed, PhD Physiotherapy

  University of Lahore

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: This study will use a single-blind masking design, in which the outcome assessor will be blinded to group allocation. Participants and therapists will be aware of the intervention assigned, but the assessor responsible for data collection and analysis will not have access to group assignment information to minimize assessment bias.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: This study follows a parallel group design, involving two groups: a control group and an experimental group. Participants in both groups will receive treatment concurrently but under different conditions. The control group will receive the standard or conventional intervention, while the experimental group will receive the modified or additional treatment being investigated. Comparisons between the groups will be made to evaluate the effectiveness of the experimental intervention.

Study Record Dates

• First Submitted: November 17, 2025
• First Posted: November 24, 2025
• Study Start: June 1, 2023
• Primary Completion: June 1, 2024
• Study Completion: July 1, 2024
• Last Updated: November 24, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP
• Time Frame: Three years after the publication of result findings
• Access Criteria: Access to the de-identified individual participant data (IPD) and supporting documents will be available to qualified researchers affiliated with recognized academic or research institutions. Interested researchers may request access by submitting a written proposal outlining the study objectives and analysis plan to the principal investigator or corresponding author. Upon approval, the data (including de-identified participant-level datasets, study protocol, and statistical analysis plan) will be shared via a secure institutional data repository or encrypted email. Data will be provided solely for non-commercial, academic research purposes and must comply with applicable ethical and data protection standards.

Locations

PA (1)