Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life

NCT07243054 | Recruiting

• 1 other identifier: PI2025_843_0037
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

At birth, the infant's weight was measured daily to assess the adequacy of nutritional intake. This indicator can be influenced by various factors related to the mother, her pregnancy, as well as medical interventions during the pre-delivery phase, such as pre-partum maternal fluid intakes, and the subsequent feeding method chosen for the newborn infant. This study aimed at exploring the association between maternal vascular fluid loading during labor in the pre-partum period and neonatal weight loss in the first two days of life. The study focuses on infants fedded with infant formula. This observational, retrospective, single-center study was carried out at the Amiens University Hospital Center. The participants were mothers aged 18 and older, hospitalized in the maternity ward following full-term delivery (\> 37 weeks of gestation). Data were collected through the medical records of the patient and their newborn. The investigators hypothesize that a relationship may exist between maternal pre-partum vascular fluid loading and neonatal weight loss in the first two days of life, in infants fed with infant formula. These results could raise awareness and help adapt medical and parental approaches to neonatal weight loss.

Conditions

Vascular Filling; Newborn; Weight Loss; Jaundice; Respiratory Distress

Keywords

vascular filling; newborn; weight loss; jaundice; respiratory distress

Outcome Measures

Primary Outcomes (1)

• Correlation between maternal vascular fluid loading and newborn infant weight loss

  2 days

Secondary Outcomes (2)

• Correlation between maternal vascular fluid loading and respiratory distress

  2 days

• Correlation between maternal vascular fluid loading and jaundice of the newborn

  2 days

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: Mother over 18 years of age and newborn
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Mother over 18 years of age and newborn

You may qualify if:

• Full-term delivery (≥37+0 SA)
• Singleton pregnancy
• Mother over 18 years of age
• Infant formula feeding exclusively in the maternity ward for the first 2 days

You may not qualify if:

• Mother under guardianship
• Mother who does not understand French
• Mother objecting to her personal data being reused for research purposes
• Incomplete or incorrectly completed patient medical record
• Mixed or exclusive breastfeeding
• Mother presenting a hemodynamic disorder in the 12 hours preceding delivery, requiring a filling specifically for this reason
• Child with renal pathology or uropathy
• Children with cleft lip, palate or labio-palate

Sponsors & Collaborators

• Centre Hospitalier Universitaire, Amiens: lead

Study Sites (1)

CHU Amiens Picardie

Amiens, Picardie, 80054, France

RECRUITING

MeSH Terms

Conditions

Weight Loss; Jaundice; Dyspnea

Condition Hierarchy (Ancestors)

Body Weight Changes; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Hyperbilirubinemia; Pathologic Processes; Skin Manifestations; Respiration Disorders; Respiratory Tract Diseases; Signs and Symptoms, Respiratory

Central Study Contacts

Pierre Tourneux, Pr

CONTACT

33+3 22 08 76 04; Tourneux.Pierre@chu-amiens.fr

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 17, 2025
• First Posted: November 21, 2025
• Study Start: March 1, 2025
• Primary Completion: November 1, 2025
• Study Completion: November 1, 2025
• Last Updated: November 21, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)