NCT07242261|Not Yet Recruiting
Non-invasive Characterisation of Oral Carcinomas in Patients With Fanconi Anaemia
Fanc-Oral
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Fanc-Oral
Sponsor study identifier
interventional
115
0 countries
N/A
Study Start
April 1, 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
April 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
October 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Patients with Fanconi anaemia have an increased risk of developing squamous cell carcinoma of the head and neck. In addition, their genetic vulnerability limits the use of genotoxic treatments such as radiotherapy and chemotherapy, due to increased exposure to severe toxicities. Less invasive diagnostic techniques, such as brush biopsies, which rely on cytological and ploidy analysis, offer the possibility of more systematic, comprehensive and less painful oral mapping, thereby facilitating earlier diagnosis.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
October 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
November 17, 2025
Actual (reported)November 21, 2025
Actual (reported)April 1, 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
April 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
October 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Oral brushing
* "Positive" result: presence of dysplastic cells at the moderate dysplasia stage or malignant cells. * "Negative" result: absence of dysplastic cells beyond the mild dysplasia stage and absence of malignant cells.
Day 0
oral lesion biopsy
Day 0
oral brushing of all oral lesions
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
First Submitted
November 17, 2025
First Posted
November 21, 2025
Study Start
April 1, 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
April 1, 2030
EstimatedContact the study team to confirm eligibility.
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
October 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
November 21, 2025
Record last verified: 2025-10
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Source: ClinicalTrials.gov.
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