Clinical Evaluation Comparing Tunneled Coronally Advanced Flap and Modified Coronally Advanced Tunnel With Connective Tissue Graft for Managing Single Gum Recession

NCT07239180 | Not Yet Recruiting

• 1 other identifier: CairoU PhD protocol for Khaled
• Study Type: interventional
• Target: 24
• Locations: 0 countries
• Sites: N/A

Brief Summary

The technique under investigation aims to provide effective root coverage while offering the advantage of being less invasive.

Conditions

Single Recession Defects (RT2)

Keywords

Single Recession defects (RT2); TCAF; MCAT; Clinical performance; Root Coverage; Gingival Recession

Outcome Measures

Primary Outcomes (1)

• Gingival Recession Depth (GRD)

  Measuring gingival recession depth (GRD) using UNC Periodontal probe in millimeter (mm)

  6 months

Secondary Outcomes (12)

• The Percentage of Mean Root Coverage (MRC %)

  6 months

• Complete Root Coverage (CRC)

  6 months

• Root Coverage Esthetic Score (RES)

  6 months

• The Distance between the contact point and the top of the papilla (DCP)

  6 months

• Gingival Recession Width (RW)

  6 months

Study Arms (2)

Modified Coronally Advanced Tunnel with Connective Tissue Graft

ACTIVE COMPARATOR

Procedure: Modified Coronally Advanced Tunnel with Connective Tissue Graft

Tunneled Coronally Advance Flap (TCAF) with Connective Tissue Graft

EXPERIMENTAL

Procedure: Tunneled Coronally Advance Flap with Connective Tissue Graft

Interventions

Modified Coronally Advanced Tunnel with Connective Tissue Graft PROCEDURE

Modified coronally advanced tunnel with connective tissue graft without vertical releasing incisions

Modified Coronally Advanced Tunnel with Connective Tissue Graft

Tunneled Coronally Advance Flap with Connective Tissue Graft PROCEDURE

Tunneled coronally advance flap with connective tissue graft with one vertical releasing incision

Tunneled Coronally Advance Flap (TCAF) with Connective Tissue Graft

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with single RT2 gingival recession defect ≥ 2 mm
• Age \>18 years old.
• Systemically healthy patients with no contraindications for periodontal surgeries.
• Gingival and plaque index less than 20%.
• No previous surgeries at the defect site.
• Accepts 6 months follow-up period (compliant patients).

You may not qualify if:

• RT1 gingival recession.
• Smokers \>10 cigarettes a day a contraindicating for any plastic periodontal surgery.
• Poor oral hygiene.
• Active periodontitis patients.
• Patients on medications causing gingival enlargement.
• Pregnancy.
• Teeth mobility ≥ 1 mm.
• Patients using fixed or removable orthodontic appliances.
• Restoration and/or periapical radiolucency at the defect site.

Sponsors & Collaborators

• Cairo University: lead

Related Links

• Related Info

MeSH Terms

Conditions

Gingival Recession

Condition Hierarchy (Ancestors)

Gingival Diseases; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Periodontal Atrophy

Central Study Contacts

Khaled Hashem Kamal, Masters Degree

CONTACT

00201281033350; khaled.hashem@dentistry.cu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Bachelor Degree

Study Record Dates

• First Submitted: November 16, 2025
• First Posted: November 20, 2025
• Study Start: December 14, 2025
• Primary Completion: March 30, 2026
• Study Completion (Estimated): August 30, 2026
• Last Updated: November 26, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will share