Benign Versus Malignant Causes of Intussuception in Adults
1 other identifier
interventional
35
1 country
1
Brief Summary
The aim of this study is to evaluate adult intussecption :
- Prevalence of benign vs malignant causes.
- Distribution by anatomical type.
- Clinical presentation patterns.
- Diagnostic accuracy of imaging.
- Surgical approach and outcomes.
- Length of hospital stay, complications, recurrence
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Dec 2025
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 16, 2025
CompletedFirst Posted
Study publicly available on registry
November 20, 2025
CompletedStudy Start
First participant enrolled
December 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 1, 2027
November 20, 2025
November 1, 2025
2 years
November 16, 2025
November 16, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
prevalence of benign versus malignant causes
Histopathological examination of resected bowel specimens will determine whether the cause of intussusception is benign (e.g., lipoma, polyp) or malignant (e.g., adenocarcinoma, lymphoma). The frequency and percentage of each category will be calculated
2 weeks after surgical resection
Secondary Outcomes (1)
Correlation between preoperative imaging findings and histopathological results Description
At the time of diagnosis (preoperative period )
Other Outcomes (1)
Operative findings
During intraoperative period
Study Arms (1)
Adult patient with intussusception
OTHERAdult patient with intussusception will undergo surgical resection followed byhistopathological evaluation to determine the underlying causes ( benign or malignant )
Interventions
Adult patient diagnosed with intussusception will undergo surgical resection of affected bowel segment under general anathesia . the resected specimens will be sent for histopathological evalution to determine the underlying cause , whether benign (e.g lipoma , polyp )or malignant (e.g adenocarcinama , lymphoma ). operative finding , postoperative outcome , and pathology results will be recorded and analyzed
Eligibility Criteria
You may qualify if:
- Age ≥ 19 years.
- Confirmed diagnosis of intussusception by: Imaging (CT , ultrasound , or barium studies) Intraoperative findings,
You may not qualify if:
- Patients with incomplete records or lost to follow-up
- Intussusception diagnosed radiologically but resolved spontaneously without confirmatory intervention or follow-up
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of general surgury Assiut uneversity hospital
Asyut, Egypt
Related Publications (1)
Su T, He L, Zhou T, Wu M, Guo Y, Wang Q, Jiang J, Cao X. Most Adult Intussusceptions are Caused by Tumors: A Single-Centre Analysis. Cancer Manag Res. 2020 Oct 12;12:10011-10015. doi: 10.2147/CMAR.S268921. eCollection 2020.
PMID: 33116857BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr
Study Record Dates
First Submitted
November 16, 2025
First Posted
November 20, 2025
Study Start
December 1, 2025
Primary Completion (Estimated)
December 1, 2027
Study Completion (Estimated)
December 1, 2027
Last Updated
November 20, 2025
Record last verified: 2025-11
Data Sharing
- IPD Sharing
- Will not share