Selenium Levels in Patients With Abdominal Aneurysm

NCT07236281 | Active Not Recruiting

• 1 other identifier: EK 1/11/2024
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Retrospective study comparing the selenium level in patients with abdominal aortic aneurysm with the selenium level in patients in the control group, i.e., patients without aneurysmal changes of the abdominal aorta.

Conditions

Abdominal Aneurysm; Selenium Deficiency

Keywords

abdominal aortic aneurysm; selenium deficiency

Outcome Measures

Primary Outcomes (1)

• Odds Ratio

  Odds Ratio - odds of having lower than normal selenium levels in cases compared to the same odds in controls

  From enrollment to 12 months after enrollment

Study Arms (2)

Cases - persons with abdominal aortic aneurysm

Persons with abdominal aortic aneurysm (AAA) of minimally 35 mm diameter, followed by vascular surgery outpatient office. AAA is verified by radiology, was not treated by surgical or endovascular intervention.

Controls - persons without abdominal aortic aneurysm

Persons without abdominal aortic aneurysm (AAA), as confirmed by ultrasonography. Controls will be recruited from vascular surgery outpatient office, in treatment for other vascular conditions.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study group comprises of 40 subjects. Twenty are cases, these are patients with AAA that was confirmed by radiology. The AAA was not treated by surgery or endovascular intervention. The are followed for the AAA by vascular surgery outpatient office. Controls are twenty persons without AAA, as confirmed by ultrasonography. They are followed by vascular surgery outpatient office for other vascular diseases. Both cases and controls are taken a blood sample, in which blood selenium level is established. Odds ratio will be calculated of having low than normal blood selenium levels in cases versus controls.

You may qualify if:

• cases - patients with AAA (confirmed by radiology) followed by vascular surgery outpatient office that signed informed consent. The AAA was not treated by surgery or endovascular intervention
• controls - people without AAA (confirmed by ultrasonography) followed by vascular surgery outpatient office for other vascular disease that signed informed consent

You may not qualify if:

• patients that had AAA treated by surgery or endovascular intervention
• persons that did not sign informed consent

Sponsors & Collaborators

• Comenius University: lead
• University Hospital Bratislava: collaborator

Study Sites (1)

University Hospital Bratislava

Bratislava, 85107, Slovakia

Location

MeSH Terms

Conditions

Aortic Aneurysm, Abdominal

Condition Hierarchy (Ancestors)

Aortic Aneurysm; Aneurysm; Vascular Diseases; Cardiovascular Diseases; Aortic Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chair of Institute of Epidemiology, Faculty of Medicine

Study Record Dates

• First Submitted: November 15, 2025
• First Posted: November 19, 2025
• Study Start: January 15, 2025
• Primary Completion: September 15, 2025
• Study Completion (Estimated): June 30, 2026
• Last Updated: November 19, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

SL (1)