Effect of a Music Intervention in Reducing Distress and Pain in Patients With Lung Cancer Undergoing Mini-invasive Surgery

NCT07235098 | Not Yet Recruiting

• 1 other identifier: IOSI-MUSICAL-001
• Study Type: interventional
• Target: 74
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims at evaluating whether music therapy intervention is effective in decreasing psychological (distress) and physical symptoms (pain) in patients with suspected or diagnosed lung cancer undergoing minimally invasive lung surgery.

Conditions

Lung Cancer (Suspected or Confirmed)

Keywords

lung cancer; pain; anxiety; music

Outcome Measures

Primary Outcomes (2)

• Level of distress

  Change of the level of distress on the Distress thermometer

  From the day of surgery until the day of discharge from the hospital (in average 6 days after surgery)

• Pain intensity

  Change of pain intensity on the numerical scale

  From the day of surgery until the day of discharge from the hospital (in average 6 days after surgery)

Secondary Outcomes (2)

• Serum cortisol levels

  From the day of surgery until the day of discharge from the hospital (in average 6 days after surgery)

• Additional doses of analgesics for pain control

  From the day of surgery until the day of discharge from the hospital (in average 6 days after surgery)

Study Arms (2)

Arm A treated with classical music therapy and standard of care

EXPERIMENTAL

Patients with suspected or diagnosed lung cancer undergoing minimally invasive lung resection will be treated with classical music therapy and standard of care.

Other: Music therapy intervention

Arm B treated with standard of care only

NO INTERVENTION

Patients with suspected or diagnosed lung cancer undergoing minimally invasive lung resection will be treated with standard of care only.

Interventions

Music therapy intervention OTHER

Patient randomized to experimental Arm A will receive a classical music therapy intervention throughout the duration of their hospital stay for a minimally invasive lung resection.

Arm A treated with classical music therapy and standard of care

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Suspected or confirmed diagnosis of lung cancer
• Age ≥ 18 years
• Indication for lung resection through a minimally invasive surgery
• Signed written informed consent

You may not qualify if:

• Endocrinological disorders involving cortisol axis
• Chronic steroid intake \> 10 mg/day
• Concomitant treatment with drugs against symptomatic anxiety and/or depression
• Partial or complete hearing loss
• Inability to follow the schedule of investigation
• Patient unwilling to refrain from actively listening to other music (e.g., via other personal devices/headphones) outside of the prescribed musical intervention defined by the study protocol during the hospitalization.

Sponsors & Collaborators

• Oncology Institute of Southern Switzerland: lead

Study Sites (1)

Oncology Institute of Southern Switzerland (IOSI)

Bellinzona, Canton Ticino, 6500, Switzerland

Location

MeSH Terms

Conditions

Lung Neoplasms; Pain; Anxiety Disorders

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders

Central Study Contacts

Patrizia Froesch, MD

CONTACT

+41 91 811 48 40; patrizia.froesch@eoc.ch

Luigi Tortola, PhD

CONTACT

+41 91 811 96 68; luigi.tortola@eoc.ch

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: This is a monocentric open-label randomized controlled clinical trial with two arms: * Arm A: classical music therapy + standard of care (SOC) * Arm B: SOC only Patients scheduled for minimally invasive lung resection, with a suspected or confirmed diagnosis of lung cancer, will be enrolled and randomized to one of the two arms of the study.

Study Record Dates

• First Submitted: November 14, 2025
• First Posted: November 19, 2025
• Study Start: December 15, 2025
• Primary Completion (Estimated): December 31, 2027
• Study Completion (Estimated): December 31, 2027
• Last Updated: November 19, 2025

Record last verified: 2025-11

Locations

CH (1)