Public Policy Evaluation: the Case of the Green Prescription

NCT07234617 | Recruiting

• 1 other identifier: 9588
• Study Type: interventional
• Target: 210
• Locations: 1 country
• Sites: 1

Brief Summary

Numerous studies have highlighted the harmful effects of pesticide exposure during the prenatal period. Food is one of the main vectors of exposure to pesticides, particularly glyphosate, which is the most widely used herbicide. Observational studies have highlighted their effects on health, but few interventional studies have been conducted to identify effective interventions to reduce or eliminate environmental risks. In 2022, the City of Strasbourg implemented the "Ordonnance Verte" (Green Prescription) program, giving all pregnant women in the city access to a weekly basket of organic and local vegetables for several months, as well as awareness-raising workshops on endocrine disruptors and healthy eating. The objective of this study is to assess whether this type of program reduces pregnant women's exposure to pesticides compared to women who continue to eat according to their usual habits. If conclusive, this type of assessment would play a key role in facilitating the rollout of similar initiatives on a larger scale and protecting the health of pregnant women and future children.

Conditions

Pregnancy

Keywords

Pesticides; organic vegetables

Outcome Measures

Primary Outcomes (2)

• Change in urinary pesticide concentrations over the two-week study period in the intervention group

  Measured as the difference in pesticide levels before and after the intervention

  Day 0 and at 2 weeks

• Difference in urinary pesticide concentrations between the two groups

  Measured as the difference in pesticide levels in intervention vs. control groups

  Day 0 and at 2 weeks

Study Arms (2)

Control

NO INTERVENTION

Vegetable consumption according to habits

Intervention

EXPERIMENTAL

Consumption of organic vegetables

Behavioral: Consumption of organic vegetables

Interventions

Consumption of organic vegetables BEHAVIORAL

Consumption of organic vegetables or non-organic for control group (according to their usual habits) for 2 weeks

Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Be a woman
• Be less than 32 weeks pregnant
• Be registered with the "Ordonnance Verte" program
• Have agreed, when registering for the program, to be contacted by a research team
• Be affiliated with a social security system or be a beneficiary of such a system.
• Be fluent in French.
• Be over 18 years of age
• Be able to understand the objectives and risks associated with the research and give dated and signed informed consent
• Have a telephone and internet access

You may not qualify if:

• Participation in a study on nutrition or any other studies likely to affect exposure to the compounds under investigation
• Inability to provide informed consent (difficulties in understanding on the part of the pregnant woman, etc.)
• Being under judicial protection
• Being under guardianship or conservatorship
• Working in the agricultural sector (farmer, employee, apprentice)
• Living with someone who works in the agricultural sector (farmer, employee, apprentice)

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Hôpitaux Universitaires de Strasbourg

Strasbourg, 67000, France

RECRUITING

Central Study Contacts

Virginie COLLIN-BUND, MD

CONTACT

+33 3 88 12 63 41; virginie.bund@chru-strasbourg.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 14, 2025
• First Posted: November 18, 2025
• Study Start: November 10, 2025
• Primary Completion (Estimated): August 1, 2027
• Study Completion (Estimated): August 1, 2027
• Last Updated: November 19, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)