Distal Radial Fractures in Adult Patients: 4 Weeks Versus 6 Weeks of Cast Immobilization

NCT07234370 | Enrolling By Invitation

• 1 other identifier: R.C-LNH-Orthpedics-05/2025/52
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Post-intervention outcomes comparing casting in distal radius fractures of four weeks versus six weeks.

Conditions

Fracture Forearm; Radius Distal Fracture

Outcome Measures

Primary Outcomes (5)

• Quick Disability of Arm, Shoulder, and Hand Score (Quick DASH)

  Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.

  Four weeks (Cast Removal)

• Quick Disability of Arm, Shoulder, and Hand (Quick DASH)

  Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.

  Six weeks (Cast Removal)

• Quick Disability of Arm, Shoulder, and Hand (Quick DASH)

  Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.

  3 months after cast removal

• Quick Disability of Arm, Shoulder, and Hand (Quick DASH)

  Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.

  6 months after cast removal

• Disability of Arm, Shoulder, and Hand Score

  The Disability of Arm, Shoulder, and Hand Score (DASH) is a 30-item questionnaire with scores ranging from 1 to 5 for each item. The final scores are formulated from 0 to 100, where a higher score indicates greater disability and a lower score indicates little to no disability.

  6 months post-removal of cast immobilizations

Secondary Outcomes (4)

• Radial Deviation

  6 months post-cast immobilization removal

• Ulnar Deviation

  6 months post-cast immobilization removal.

• Dorsiflexion

  6 months post-cast immobilization removal.

• Palmar Flexion

  6 months post-cast immobilization removal.

Study Arms (2)

Cast immobilization for four weeks

EXPERIMENTAL

Scotch cast immobilization for a period of four weeks applied to distal radius fractures.

Procedure: Short Arm Cast for Distal Radius Fracture for four weeks

Cast immobilization for six weeks

ACTIVE COMPARATOR

Scotch cast immobilization for a period of six weeks applied to distal radius fractures

Procedure: Short Arm Cast for Distal Radius Fracture for six weeks

Interventions

Short Arm Cast for Distal Radius Fracture for four weeks PROCEDURE

Scotch cast immobilization below elbow for four weeks

Also known as: Splint, Cast

Cast immobilization for four weeks

Short Arm Cast for Distal Radius Fracture for six weeks PROCEDURE

Scotch cast immobilization below elbow for six weeks

Also known as: Splint, Cast

Cast immobilization for six weeks

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients with DRF undergoing conservative management with cast immobilization
• Age between 18 to 50 years.

You may not qualify if:

• Any syndromic patients
• Any patients with musculoskeletal disease
• Patients having osteoporosis
• Post-menopausal females
• Smokers
• Ages less than 18 or greater than 50
• Patients presenting with intra-articular fractures

Sponsors & Collaborators

• Liaquat National Hospital & Medical College: lead

Study Sites (1)

Liaquat National Hospital

Karachi, Sindh, 74800, Pakistan

Location

MeSH Terms

Conditions

Wrist Fractures

Interventions

Splints; POLR1G protein, human

Condition Hierarchy (Ancestors)

Wrist Injuries; Arm Injuries; Wounds and Injuries; Fractures, Bone

Intervention Hierarchy (Ancestors)

External Fixators; Orthopedic Fixation Devices; Orthopedic Equipment; Surgical Equipment; Equipment and Supplies; Surgical Fixation Devices

Study Officials

• Mohammad Nabeel Aamir Syed, MBBS, MD

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Doctor

Study Record Dates

• First Submitted: November 14, 2025
• First Posted: November 18, 2025
• Study Start: September 15, 2025
• Primary Completion: December 1, 2025
• Study Completion: February 1, 2026
• Last Updated: November 24, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)