NCT07228936

Brief Summary

This study investigates whether tightness of a small chest muscle called the pectoralis minor is associated with the development of rotator cuff tears in the shoulder. Using a propensity score matched case-control design, the study compares patients with rotator cuff tears (case group, n=45) to patients with intact rotator cuffs (control group, n=45). Adults aged 18-55 with shoulder pain who are evaluated by MRI and/or shoulder arthroscopy at Gazi University Hospital may be invited. The case group includes patients found to have rotator cuff tears during arthroscopy. The control group includes patients whose rotator cuff was documented as intact by MRI and/or arthroscopy (e.g., patients treated for labral, SLAP, or instability pathology). Groups are matched 1:1 on age, sex, BMI, occupation, sportive activity and dominant side. Before surgery, a trained clinician measures shoulder posture and pectoralis minor length using simple external tools (a digital caliper and ruler-like square). For arthroscopy patients, the surgeon records general arthroscopic findings. No extra procedures are added for research. We expect to include 90 participants total. The primary hypothesis is that pectoralis minor tightness is more prevalent in patients with rotator cuff tears compared to controls. A secondary hypothesis is that tears in patients with pectoralis minor tightness more often begin on the bursal side. Results may help clinicians understand shoulder mechanics and improve prevention or rehabilitation strategies.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
90

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 18, 2025

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

November 13, 2025

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 14, 2025

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 25, 2026

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2026

Completed
Last Updated

May 28, 2026

Status Verified

April 1, 2026

Enrollment Period

1.2 years

First QC Date

November 13, 2025

Last Update Submit

May 23, 2026

Conditions

Keywords

rotator cuffRotator Cuff InjuriesPostureScapulaPectoralis MusclesArthroscopyShoulder JointPectoralis Minor

Outcome Measures

Primary Outcomes (1)

  • Pectoralis minor muscle length difference between case and control groups

    Comparison of pectoralis minor (PM) muscle length (mm) between patients with rotator cuff tears (case group) and patients with intact rotator cuffs (control group). PM length is measured as the linear distance from coracoid tip to rib attachment using a digital caliper. Primary analysis: conditional logistic regression evaluating whether PM tightness is associated with rotator cuff tear presence in propensity score matched pairs.

    Preoperative assessment, Day 0

Secondary Outcomes (5)

  • Tear initiation site in the case group

    Intraoperative, Day 0 (index arthroscopy)

  • Forward shoulder posture

    Preoperative assessment, Day 0

  • Medial Scapular Border Thoracic Distance

    Preoperative assessment, Day 0

  • Thoracic Kyphosis (Cobb angle)

    Preoperative imaging review, Day 0

  • Scapular index (Coracoid-Sternum/Acromian lateral tip - thoracic spine)

    Preoperative assessment, Day 0

Study Arms (2)

Rotator Cuff Tear (Case)

Patients who underwent shoulder arthroscopy and were found to have rotator cuff tears during surgery. Pectoralis minor length, medial scapular distance, and forward shoulder posture were measured preoperatively. Propensity score matched 1:1 with the control group on age, sex, BMI, and dominant side.

Intact Rotator Cuff (Control)

Patients presenting with shoulder pain whose rotator cuff was documented as intact by MRI and/or intraoperative arthroscopy findings. Includes patients who underwent arthroscopy for labral, SLAP, or instability pathology without rotator cuff tear, and patients with MRI-confirmed intact rotator cuff. Propensity score matched 1:1 with the case group on age, sex, BMI, and dominant side.

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Adult patients (18-55 years) receiving care at a tertiary orthopaedic shoulder service (Gazi University Hospital, Ankara, Türkiye). Case group: patients who underwent shoulder arthroscopy and were found to have partial- or full-thickness rotator cuff tears. Control group: patients with shoulder pain whose rotator cuff integrity was confirmed intact by MRI and/or arthroscopy. Groups are propensity score matched 1:1 on age, sex, BMI, and dominant side.

You may qualify if:

  • Adults 18 to 55 years old.
  • Shoulder pain.
  • Evaluated by MRI and/or shoulder arthroscopy.
  • Willing to take part and give informed consent.

You may not qualify if:

  • Previous surgery on the same shoulder.
  • Recent traumatic shoulder injury such as fracture or dislocation.
  • Rotator cuff tear due to major trauma.
  • Neck/nerve conditions affecting the shoulder, such as cervical radiculopathy or thoracic outlet syndrome.
  • Systemic inflammatory joint disease, such as rheumatoid arthritis or ankylosing spondylitis.
  • Cognitive or communication problems that would prevent accurate measurements or consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gazi University Hospital

Ankara, Cankaya, 06500, Turkey (Türkiye)

RECRUITING

Related Publications (9)

  • Kibler WB, McMullen J. Scapular dyskinesis and its relation to shoulder pain. J Am Acad Orthop Surg. 2003 Mar-Apr;11(2):142-51. doi: 10.5435/00124635-200303000-00008.

    PMID: 12670140BACKGROUND
  • Yamaguchi K, Ditsios K, Middleton WD, Hildebolt CF, Galatz LM, Teefey SA. The demographic and morphological features of rotator cuff disease. A comparison of asymptomatic and symptomatic shoulders. J Bone Joint Surg Am. 2006 Aug;88(8):1699-704. doi: 10.2106/JBJS.E.00835.

    PMID: 16882890BACKGROUND
  • Cools AM, Struyf F, De Mey K, Maenhout A, Castelein B, Cagnie B. Rehabilitation of scapular dyskinesis: from the office worker to the elite overhead athlete. Br J Sports Med. 2014 Apr;48(8):692-7. doi: 10.1136/bjsports-2013-092148. Epub 2013 May 18.

    PMID: 23687006BACKGROUND
  • Borstad JD, Ludewig PM. The effect of long versus short pectoralis minor resting length on scapular kinematics in healthy individuals. J Orthop Sports Phys Ther. 2005 Apr;35(4):227-38. doi: 10.2519/jospt.2005.35.4.227.

    PMID: 15901124BACKGROUND
  • Oyama S, Myers JB, Wassinger CA, Daniel Ricci R, Lephart SM. Asymmetric resting scapular posture in healthy overhead athletes. J Athl Train. 2008 Oct-Dec;43(6):565-70. doi: 10.4085/1062-6050-43.6.565.

    PMID: 19030133BACKGROUND
  • Ludewig PM, Reynolds JF. The association of scapular kinematics and glenohumeral joint pathologies. J Orthop Sports Phys Ther. 2009 Feb;39(2):90-104. doi: 10.2519/jospt.2009.2808.

    PMID: 19194022BACKGROUND
  • Peterson DE, Blankenship KR, Robb JB, Walker MJ, Bryan JM, Stetts DM, Mincey LM, Simmons GE. Investigation of the validity and reliability of four objective techniques for measuring forward shoulder posture. J Orthop Sports Phys Ther. 1997 Jan;25(1):34-42. doi: 10.2519/jospt.1997.25.1.34.

    PMID: 8979174BACKGROUND
  • Du WY, Huang TS, Hsu KC, Lin JJ. Measurement of scapular medial border and inferior angle prominence using a novel scapulometer: A reliability and validity study. Musculoskelet Sci Pract. 2017 Dec;32:120-126. doi: 10.1016/j.msksp.2017.08.004. Epub 2017 Aug 15.

    PMID: 28827031BACKGROUND
  • Borstad JD. Measurement of pectoralis minor muscle length: validation and clinical application. J Orthop Sports Phys Ther. 2008 Apr;38(4):169-74. doi: 10.2519/jospt.2008.2723. Epub 2007 Nov 21.

    PMID: 18434665BACKGROUND

MeSH Terms

Conditions

Shoulder Impingement SyndromeRotator Cuff Injuries

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal DiseasesShoulder InjuriesWounds and InjuriesRuptureTendon Injuries

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
STUDY CHAİR GAZİ UNİVERSİTY

Study Record Dates

First Submitted

November 13, 2025

First Posted

November 14, 2025

Study Start

March 18, 2025

Primary Completion

May 25, 2026

Study Completion

May 30, 2026

Last Updated

May 28, 2026

Record last verified: 2026-04

Locations