Assesment and Comparison of Osteoporosis Risk Factors After Stroke

NCT07228611 | Recruiting

• 1 other identifier: AEŞH-BADEK-2025-478
• Study Type: observational
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to evaluate the effect of these factors and stroke itself on osteoporosis developing after stroke. Thus, the expected benefit of the study is to contribute to the identification and determination of the need for treatment in high-risk patients through further studies. There are no expected risks from the study.

Conditions

Stroke Osteoporosis

Outcome Measures

Primary Outcomes (1)

• Bone Mineral Density

  First day of hospitalization

Secondary Outcomes (7)

• Brunnstrom

  First day of hospitalization

• Modified Barthel Index

  First day of hospitalization

• Modified Ashworth Scale

  First day of hospitalization

• Modified Fall Impact Scale

  First day of hospitalization

• Vitamin D, prealbumin, and albumin

  First day of hospitalization

Study Arms (3)

Subacute Stroke

Diagnostic Test: Bone Mineral Density

Chronic Stroke

Diagnostic Test: Bone Mineral Density

Healthy Volunteer

Diagnostic Test: Bone Mineral Density

Interventions

Bone Mineral Density DIAGNOSTIC_TEST

Patients who have had a stroke and are at risk of fracture, and for whom routine assessment requires Bone Mineral Density (BMD) testing, will be included in the study. In addition, patients who have already undergone BMD testing for osteoporosis screening and who present to the outpatient clinic, with similar age and comorbidities, will be screened from the system, and 28 non-stroke patients who agree to participate will be included in the study.

Chronic Stroke; Healthy Volunteer; Subacute Stroke

Eligibility Criteria

• Age: 55 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Fifty-six stroke patients receiving inpatient treatment will be evaluated. In addition, patients who have visited the outpatient clinic and have already undergone BMD scanning for osteoporosis screening, with similar age and comorbidities, will be screened from the system, and 28 non-stroke patients who agree to participate will be randomly included in the study.

You may qualify if:

• Followed by ischemic or hemorrhagic stroke
• Between 1 week and 6 months or \>1 year has passed since the date of the event
• Being between 55 and 85 years of age

You may not qualify if:

• The patient has additional neurological conditions besides stroke
• The patient has a psychiatric condition
• History of recurrent stroke
• BMD scan performed within the last year for stroke patients
• Having received osteoporosis treatment before or after the stroke
• The patient having a fragility fracture before the stroke
• The patient having a hip fracture or hip prosthesis
• The patient having an additional condition that affects physical function before the stroke (amputation, severe fracture)
• The patient has an additional disease or medication use that could cause secondary osteoporosis
• The patient's stroke did not cause physical function loss

Sponsors & Collaborators

• Ankara Etlik City Hospital: lead

Study Sites (1)

Ankara Etlik City Hospital

Ankara, Yenimahalle, 06010, Turkey (Türkiye)

RECRUITING

MeSH Terms

Interventions

Bone Density

Intervention Hierarchy (Ancestors)

Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Central Study Contacts

Ayşe Naz Kalem Özgen, specialist

CONTACT

+90 0312 797 00 00; kalemnaz@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PM&R Specialist

Study Record Dates

• First Submitted: November 13, 2025
• First Posted: November 14, 2025
• Study Start: December 5, 2025
• Primary Completion: May 1, 2026
• Study Completion: May 1, 2026
• Last Updated: February 24, 2026

Record last verified: 2025-11

Locations

TU (1)