The Effects of Demographic and Clinical Data of Patients on Cerebral Oxygen Monitoring Values

NCT07228546 | Completed

• 1 other identifier: Adana City TRH
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to examine the effects of patients' clinical and demographic datas on cerebral oxygen saturation values. Brain oxygenation is measured using near infrared spectroscopy (NIRS). The primary outcome measure of the study is the regional oxygen saturation (rSO2) values measured on the monitor at twelve time points. The other primary outcome measures consist of baseline arterial and venous blood gas analysis and baseline activated clotting time measurements.

Conditions

Cerebral Oxygen Saturation

Keywords

near infrared spectroscopy; coronary artery bypass grafting; regional cerebral oxygen saturation

Outcome Measures

Primary Outcomes (4)

• Regional oxygen saturation values

  Regional oxygen saturation values measurement at twelve points.

  Baseline and peroperative measurements until the and of surgery

• Baseline arterial blood gas analysis

  The baseline arterial blood gas sample taken from the patient after arterial cannulation

  Within 5 minutes after arterial cannulation for the baseline measurement

• Venous blood gas analysis

  Venous blood gas sample taken from the patient after central jugular venous cannulation

  Within 5 minutes after central jugular venous cannulation

• Baseline activated clotting time measurement

  The baseline measurement of activated clotting time after arterial cannulation

  Within 5 minutes after arterial cannulation for the baseline measurement

Eligibility Criteria

• Age: 25 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients undergoing elective coronary artery bypass grafting surgery

You may qualify if:

• Accepting to participate in the study
• Undergoing elective coronary artery bypass grafting surgery
• Age 25-80 years Ejection fraction 30% and above

You may not qualify if:

• Non volunteers
• Age \<25 or \>80 years
• Ejection fraction below 30%
• Patients with history of neurological disease or neurosurgery
• Emergency surgery
• Concurrent valve surgery
• Patients with history of carotid artery stenosis
• Patients with need for preoperative intraaortic balloon pump or inotropic support

Sponsors & Collaborators

• Tuna Şahin: lead

Study Sites (1)

Tuna Şahin

Adana, Yüreğir, 01370, Turkey (Türkiye)

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Anesthesiologist

Study Record Dates

• First Submitted: September 30, 2025
• First Posted: November 14, 2025
• Study Start: May 12, 2025
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: January 7, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)