Adjuvant Steroid Outcomes in Idiopathic Subglottic Stenosis

You may not qualify if:

• History of subglottic stenosis from identifiable cause (not idiopathic), including any of the below clinical criteria:
• Prolonged endotracheal intubation or tracheostomy (intervention greater than 7 days immediately prior to diagnosis of subglottic stenosis);
• External physical trauma (including but not limited to blunt, penetration, chemical, or thermal injury) that causes injury to the subglottis;
• Clinical diagnosis of granulomatosis with polyangiitis (GPA);
• Radiation exposure to the neck;
• Complications resulting from the Index Procedure, including needing an endotracheal tube or tracheostomy immediately following surgery or a perforation of the trachea;
• Current or previous treatment with SILSI;
• Use of systemic corticosteroids (oral, intravenous, or intramuscular glucocorticoids), regardless of indication, within 7 days before triamcinolone administration;
• Local administration of corticosteroids (ophthalmic, intranasal, inhaled) is not prohibited. However, the administration of intraarticular corticosteroids during the Study Drug Dosing phase is not recommended due to potential increased risk of infection.
• Intralesional administration, in a site other than the subglottis, of corticosteroids should be discussed with the site PI before enrollment.
• Use of inhaled steroids is permitted during the study if the participant was taking at the time of consent, and no new inhaled steroids can be started while enrolled in the study.
• Intraarticular corticosteroids during the Study Drug Dosing phase due to potential increased risk of infection;
• Use of anticoagulants other than aspirin (daily aspirin dose should not exceed 81mg);
• Pulmonary disease including interstitial lung disease or COPD/emphysema;
• Systemic infection requiring treatment with antibiotics, antifungal, or antiviral agents within 21 days of Enrollment;
• +21 more criteria