NCT07228013

Brief Summary

The goal of this feasibility study is to determine if active engagement with plants (e.g. care, maintenance) improves mental health and academic performance in college students. The main questions it aims to answer are:

  • Complete four surveys over the course of a 16-week semester
  • Water, prune and check the soil of their assigned plants

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
87

participants targeted

Target at P50-P75 for not_applicable

Timeline
8mo left

Started Aug 2025

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress52%
Aug 2025Dec 2026

Study Start

First participant enrolled

August 22, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 4, 2025

Completed
9 days until next milestone

First Posted

Study publicly available on registry

November 13, 2025

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Last Updated

January 13, 2026

Status Verified

January 1, 2026

Enrollment Period

1.4 years

First QC Date

November 4, 2025

Last Update Submit

January 12, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change in Perceived Stress from Baseline to Week 16

    The Perceived Stress Scale (PSS) is a validated, widely used measure of stress with clinical relevance in student populations. A significant reduction in Perceived Stress Scale scores would demonstrate a therapeutic effect of the intervention. Scores range from 0-40. Scores ranging from 0-13 would be considered low stress. Scores ranging from 14-26 would be considered moderate stress. Scores ranging from 27-40 would be considered high perceived stress.

    Week 2: Baseline/Time 1 Survey Week 7: Time 2 Survey Week 11: Time 3 Survey Week 16: Time 4 Survey

  • Change in Negative Affect from Baseline to Week 16

    The Negative Affect subscale of the Positive and Negative Affect Schedule captures symptoms of anxiety and distress, aligning with the study's focus on mental health. It complements the Perceived Stress Scale by measuring emotional states. Scores of the scale range from 10-50 with higher scores representing higher levels of negative affect.

    Week 2: Baseline/Time 1 Survey Week 7: Time 2 Survey Week 11: Time 3 Survey Week 16: Time 4 Survey

Secondary Outcomes (5)

  • Change in Sleep Quality from Baseline to Week 16

    Week 2: Baseline/Time 1 Survey Week 7: Time 2 Survey Week 11: Time 3 Survey Week 16: Time 4 Survey

  • Change in Perceived Anxiety from Baseline to Week 16

    Week 2: Baseline/Time 1 Survey Week 7: Time 2 Survey Week 11: Time 3 Survey Week 16: Time 4 Survey

  • Change in Perceived Mood Disturbance from Baseline to Week 16

    Week 2: Baseline/Time 1 Survey Week 7: Time 2 Survey Week 11: Time 3 Survey Week 16: Time 4 Survey

  • Change in Academic Performance from Baseline to Week 16

    Week 2: Baseline/Time 1 Survey Week 7: Time 2 Survey Week 11: Time 3 Survey Week 16: Time 4 Survey

  • Change in Connectedness to Nature from Baseline to Week 16

    Week 2: Baseline/Time 1 Survey Week 7: Time 2 Survey Week 11: Time 3 Survey Week 16: Time 4 Survey

Study Arms (3)

G1 (Comparison)

NO INTERVENTION

G2 (Campus Plant Care)

EXPERIMENTAL

Active care for 1-2 plants in shared academic spaces (e.g. classrooms, hallways)

Behavioral: Active Plant Engagement

G3 (Home Plant Care)

EXPERIMENTAL

Active care for 1-2 plants in personal living spaces (dorm/apartment)

Behavioral: Active Plant Engagement

Interventions

Weekly watering, pruning, and soil checks of assigned plants

Also known as: Hands-on Plant Care and Maintenance
G2 (Campus Plant Care)G3 (Home Plant Care)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Enrolled in in-person HES courses during the study semester
  • Not currently growing/caring for plants
  • Willing to comply with assigned intervention
  • Able to complete surveys in English
  • Available for 16-week duration

You may not qualify if:

  • Current enrollment in other intervention studies targeting mental health/academic performance
  • Severe plant allergies (e.g. to pollen, mold) regardless of the use of non-toxic and non-pollen plants

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Colorado State University Health and Exercise Science Department

Fort Collins, Colorado, 80523, United States

Location

Related Publications (6)

  • van den Bogerd N, Coosje Dijkstra S, Koole SL, Seidell JC, de Vries R, Maas J. Nature in the indoor and outdoor study environment and secondary and tertiary education students' well-being, academic outcomes, and possible mediating pathways: A systematic review with recommendations for science and practice. Health Place. 2020 Nov;66:102403. doi: 10.1016/j.healthplace.2020.102403. Epub 2020 Sep 12.

    PMID: 32932004BACKGROUND
  • Jacobson NS, Dobson KS, Truax PA, Addis ME, Koerner K, Gollan JK, Gortner E, Prince SE. A component analysis of cognitive-behavioral treatment for depression. J Consult Clin Psychol. 1996 Apr;64(2):295-304. doi: 10.1037//0022-006x.64.2.295.

    PMID: 8871414BACKGROUND
  • Deci EL, Ryan RM. Self-determination theory in health care and its relations to motivational interviewing: a few comments. Int J Behav Nutr Phys Act. 2012 Mar 2;9:24. doi: 10.1186/1479-5868-9-24.

    PMID: 22385839BACKGROUND
  • Nuss K, Moore K, Marchant T, Courtney JB, Edwards K, Sharp JL, Nelson TL, Li K. The combined effect of motivational interviewing and wearable fitness trackers on motivation and physical activity in inactive adults: A randomized controlled trial. J Sports Sci. 2023 Jan;41(1):45-55. doi: 10.1080/02640414.2023.2195228. Epub 2023 Mar 25.

    PMID: 36966352BACKGROUND
  • Ibrahim AK, Kelly SJ, Adams CE, Glazebrook C. A systematic review of studies of depression prevalence in university students. J Psychiatr Res. 2013 Mar;47(3):391-400. doi: 10.1016/j.jpsychires.2012.11.015. Epub 2012 Dec 20.

    PMID: 23260171BACKGROUND
  • Beiter R, Nash R, McCrady M, Rhoades D, Linscomb M, Clarahan M, Sammut S. The prevalence and correlates of depression, anxiety, and stress in a sample of college students. J Affect Disord. 2015 Mar 1;173:90-6. doi: 10.1016/j.jad.2014.10.054. Epub 2014 Nov 8.

    PMID: 25462401BACKGROUND

Related Links

MeSH Terms

Conditions

Anxiety DisordersSleep Initiation and Maintenance Disorders

Interventions

Maintenance

Condition Hierarchy (Ancestors)

Mental DisordersSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Intervention Hierarchy (Ancestors)

Health Care Facilities Workforce and Services

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
SUPPORTIVE CARE
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor, Director

Study Record Dates

First Submitted

November 4, 2025

First Posted

November 13, 2025

Study Start

August 22, 2025

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

January 13, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations