Spine Oncology Registry
A Prospective Registry of Patients Undergoing Surgical Decompression Followed by Radiation Therapy for Spine Tumors
3 other identifiers
observational
3,000
1 country
3
Brief Summary
This is an observational study to evaluate hardware related and oncologic outcomes in adult patients with primary and metastatic spine disease undergoing separation surgery followed by radiation treatment.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2025
Longer than P75 for all trials
3 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 14, 2025
CompletedFirst Posted
Study publicly available on registry
November 6, 2025
CompletedStudy Start
First participant enrolled
November 24, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2035
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2037
December 19, 2025
December 1, 2025
10.1 years
October 14, 2025
December 14, 2025
Conditions
Outcome Measures
Primary Outcomes (3)
Overall survival
12, 18, 24 months
Local control of treated lesion based on radiographic review
Patients will be classified as achieving local control if demonstrating response of treated spine lesion after treatment. Local control will be assessed by comparing the radiographic images after treatment and prospectively every 3 months for up to 24 months
3, 6, 9, 12, 15, 16, 21, 24 months
Progression free survival
3, 6, 9, 12, 15, 16, 21, 24 months
Eligibility Criteria
The study population will be comprised of patients with primary and metastatic spine disease who undergo surgery followed by radiation therapy. Patients may be enrolled regardless of previous local or systemic treatments received prior to enrollment in this registry. Patients may be enrolled regardless of other current local or systemic treatments of disease extent.
You may qualify if:
- Diagnosis of primary or metastatic disease to the spine who undergo surgical decompression and stabilization followed by radiation therapy
You may not qualify if:
- Inability to obtain a standard MRI or CT / CT myelogram for radiation treatment planning and dosimetry
- Inability to receive radiation treatment.
- Patients under 18 years of age
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (3)
University of Michigan
Ann Arbor, Michigan, 48109, United States
Rutgers Robert wood Johnson Medical School
New Brunswick, New Jersey, 08901, United States
The Ohio State University Wexner Medical Center
Columbus, Ohio, 43210, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
James B Elder, MD
Ohio State University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
October 14, 2025
First Posted
November 6, 2025
Study Start
November 24, 2025
Primary Completion (Estimated)
December 31, 2035
Study Completion (Estimated)
December 31, 2037
Last Updated
December 19, 2025
Record last verified: 2025-12