MOVE Protocol - Movement-Oriented Velocity of Engagement

NCT07220200 | Completed

• 1 other identifier: MOVE-001/2025
• Study Type: interventional
• Target: 40
• Locations: 2 countries
• Sites: 4

Brief Summary

A Prospective, Multi-Site, Interventional Case-Series Evaluating the MOVE (Movement-Oriented Velocity of Engagement) Protocol for Musculoskeletal Pain Recovery

Conditions

Musculoskeletal Pain - Acute and Subacute Conditions

Keywords

Rehabilitation Biomechanics Early Mobilization Movement Therapy Functional Recovery Pain Management Physical Therapy

Outcome Measures

Primary Outcomes (1)

• Pain Reduction (NRS Score)

  Change in Numeric Rating Scale (NRS) for pain intensity from baseline to week 8 following the MOVE (Movement-Oriented Velocity of Engagement) rehabilitation program. Participants rated pain on a 0-10 scale where 0 = no pain and 10 = worst possible pain.

  Baseline, Week 2, Week 4, and Week 8

Secondary Outcomes (3)

• Functional Improvement (LEFS / UEFI Score)

  Baseline, Week 2, Week 4, Week 8

• Balance and Postural Stability (Timed Single-Leg Stance Test)

  Baseline, Week 4, Week 8

• Participant Perceived Recovery (Global Rating of Change Scale)

  Week 8

Study Arms (1)

Move Protocol

EXPERIMENTAL

Participants received the MOVE (Movement-Oriented Velocity of Engagement) rehabilitation protocol, consisting of four progressive phases: Mobilize, Optimize Load, Validate Neural Control, and Energize Recovery. The program emphasized functional movement restoration, load tolerance, and neuromuscular coordination.

Behavioral: MOVE Rehabilitation Protocol

Interventions

MOVE Rehabilitation Protocol BEHAVIORAL

The MOVE (Movement-Oriented Velocity of Engagement) protocol is a biomechanics-based rehabilitation approach targeting early mobilization and functional recovery for musculoskeletal pain conditions. The structured program includes four key phases: Mobilize, Optimize Load, Validate Neural Control, and Energize Recovery, applied over 8 weeks under therapist supervision.

Move Protocol

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18-65 years diagnosed with acute or subacute musculoskeletal pain or movement restriction (≤12 weeks duration).
• Capable of performing supervised rehabilitation and daily movement tasks.
• Able to provide informed consent and comply with study assessments.
• Baseline pain score ≥4 on the Numerical Rating Scale (NRS).

You may not qualify if:

• Chronic pain (\>12 weeks) or neurological disorders affecting movement control.
• Post-surgical cases or fractures within the past 3 months.
• Cardiopulmonary or systemic illness contraindicating exercise participation.
• Pregnancy or conditions limiting safe participation in physical rehabilitation.
• Refusal to sign informed consent.

Sponsors & Collaborators

• MMSx Authority Institute for Movement Mechanics and Biomechanics Research Inc: lead

Study Sites (4)

BodyGNTX Fitness Institute

Columbus, Ohio, 43220, United States

Location

MMSx AUTHORITY (COORDINATING CENTER)

Powell, Ohio, 43065, United States

Location

Indian Institute of Kinesiology & Biomechanics Science (IIKBS)

Burhānpur, Madhya Pradesh, 450331, India

Location

GFFI Fitness Academy

New Delhi, National Capital Territory of Delhi, 110026, India

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Masking Details: Open-label rehabilitation study. Both investigators and participants were aware of the intervention procedures, as exercise-based protocols require therapist supervision and participant engagement.
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: UNKNOWN
• Responsible Party: SPONSOR

Model Details: This was a multi-site, single-arm interventional case-series evaluating the MOVE (Movement-Oriented Velocity of Engagement) rehabilitation protocol for acute and subacute musculoskeletal pain. Forty participants across four international centers completed an 8-week standardized intervention consisting of four progressive phases: Mobilize, Optimize Load, Validate Neural Control, and Energize Recovery. The study aimed to assess safety, functional recovery, and pain reduction outcomes following the MOVE protocol.

Study Record Dates

• First Submitted: October 22, 2025
• First Posted: October 23, 2025
• Study Start: June 15, 2024
• Primary Completion: October 10, 2024
• Study Completion: October 17, 2025
• Last Updated: October 23, 2025

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (2); IN (2)