Fastomics: Metabolic and Therapeutic Effects of Prolonged Fasting
1 other identifier
observational
15
1 country
1
Brief Summary
This is an observational study investigating how the metabolic and cell marker changes in Prolonged Fasting in the serum may be used against a cell-based model of disease for therapeutic purposes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Aug 2025
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 5, 2025
CompletedFirst Submitted
Initial submission to the registry
September 22, 2025
CompletedFirst Posted
Study publicly available on registry
October 15, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
October 1, 2026
October 15, 2025
October 1, 2025
1.2 years
September 22, 2025
October 13, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Feasibility of doing prolonged fasting in this population
measured by % participants completing all the visits
Day 4
Secondary Outcomes (2)
Exposure of plasma on in vitro breast cancer cell models with regards to cell viability, signaling, function, plasma metabolites, and inflammatory markers
Baseline
Exposure of plasma on in vitro breast cancer cell models with regards to cell viability, signaling, function, plasma metabolites, and inflammatory markers
After 60 hours of fasting
Study Arms (1)
60 Hour Fasting
healthy participants who agree to fast with water for up to 60 hours while wearing continuous glucose monitors
Interventions
fast with water for up to 60 hours while wearing continuous glucose monitors
Eligibility Criteria
Self-reportedly healthy subjects
You may qualify if:
- Ages of 18-65 years old
- Not pregnant
- No comorbid conditions
- BMI of 18.5-29.9.
- Has a smartphone
You may not qualify if:
- Concern for active eating disorder per screening questionnaire
- Self-reported eating disorder or history of eating disorder
- History of hypoglycemia or contraindication for Prolonged Fasting
- Weight \<120lbs
- History of blood donation within the last 3 months.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Minnesota
Minneapolis, Minnesota, 55455, United States
Biospecimen
Samples will be stored, with participant consent, deidentified in freezers under the care of the PI indefinitely
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Lisa Chow, MD, MS
University of Minnesota
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 22, 2025
First Posted
October 15, 2025
Study Start
August 5, 2025
Primary Completion (Estimated)
October 1, 2026
Study Completion (Estimated)
October 1, 2026
Last Updated
October 15, 2025
Record last verified: 2025-10