Mortality of Trauma in the Intensive Care Unit.

NCT07208110 | Not Yet Recruiting

• 1 other identifier: GRIVI_2025_01_QX_UCI_TMA
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, it was planned to establish the factors associated with severe trauma discharged from the intensive care unit and mortality. A cross-sectional trial will be conducted to review the ICU discharge database at a two-year interval to review records of trauma admissions patients and compare them with other types of admissions. Participant institutions are general hospitals (public and private) from the Colombian Orinoco region. the prevalence of admission by trauma will also be determined.

Conditions

Trauma (Including Fractures); Trauma ICU Patients; Trauma Injury; Trauma Patients in ICU; Trauma Patients

Keywords

Trauma; Wounds and Injuries; Intensive Care Units; Trauma Registry; Low-Middle Income Countries; Colombia

Outcome Measures

Primary Outcomes (1)

• Mortality

  Discharge by death or within 30 days of ICU length of stay.

  30 days

Secondary Outcomes (1)

• ICU length of stay

  30 days

Study Arms (2)

Trauma

Records of patients admitted to the ICU with a diagnosis of trauma, major trauma, polytrauma, severe trauma.

Other: Exposed to trauma

Non-trauma

Records of patients admitted to the ICU with other non-trauma diagnosis.

Other: Not exposed

Interventions

Exposed to trauma OTHER

Patients exposed to trauma previous to the admission to the ICU.

Trauma

Not exposed OTHER

Patients not exposed to trauma previous to the admission to the ICU.

Non-trauma

Eligibility Criteria

• Age: 15 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Records of patient discharged from the intensive care unit.

You may qualify if:

• Admitted to the intensive care unit.

You may not qualify if:

• None.

Sponsors & Collaborators

• Hospital Departamental de Villavicencio: lead
• Cooperative University of Colombia: collaborator
• Clínica Primavera: collaborator

Study Sites (1)

Hospital Departamental de Villavicencio

Villavicencio, Meta Department, 50001, Colombia

Location

Related Publications (6)

• Wang F, Li ZM, Ma T. Construction and validation of a nomogram prediction model for the need for intensive care unit admission after hip fracture surgery. Medicine (Baltimore). 2025 Jun 13;104(24):e42793. doi: 10.1097/MD.0000000000042793.

  PMID: 40527820 RESULT

• Valcarcel CR, Bieler D, Bass GA, Gaarder C, Hildebrand F; ESTES Polytrauma Consensus Group. ESTES recommendations for the treatment of polytrauma-a European consensus based on the German S3 guidelines for the treatment of patients with severe/multiple injuries. Eur J Trauma Emerg Surg. 2025 Apr 11;51(1):171. doi: 10.1007/s00068-025-02852-4.

  PMID: 40214785 RESULT

• Nunes Dos Santos MS, Stayt LC. The effectiveness of FOUR score versus GCS scale in predicting mortality and morbidity in traumatic brain injured patients in intensive care: A systematic review. Intensive Crit Care Nurs. 2025 Aug;89:104048. doi: 10.1016/j.iccn.2025.104048. Epub 2025 May 7.

  PMID: 40339389 RESULT

• Chen Y, Wei X, Sun X, Mo X, Tu J, Xie T. Development and validation of a practical predicting model for early mortality in polytrauma patients: secondary analysis from Switzerland. BMJ Open. 2025 Jun 12;15(6):e100417. doi: 10.1136/bmjopen-2025-100417.

  PMID: 40506077 RESULT

• Hefny AF, Idris K, Eid HO, Abu-Zidan FM. Factors affecting mortality of critical care trauma patients. Afr Health Sci. 2013 Sep;13(3):731-5. doi: 10.4314/ahs.v13i3.30.

  PMID: 24250314 RESULT

• Fukuchi M, Nakajima M, Fukai Y, Miyazaki T, Masuda N, Sohda M, Manda R, Tsukada K, Kato H, Kuwano H. Increased expression of c-Ski as a co-repressor in transforming growth factor-beta signaling correlates with progression of esophageal squamous cell carcinoma. Int J Cancer. 2004 Mar 1;108(6):818-24. doi: 10.1002/ijc.11651.

  PMID: 14712482 RESULT

MeSH Terms

Conditions

Wounds and Injuries; Accidental Injuries

Study Officials

• Norton Perez Gutierrez, MD

  Universidad Cooperativa de Colombia; Hospital Departamental de Villavicencio; Clínica Primavera

  STUDY DIRECTOR

Central Study Contacts

Norton Perez Gutierrez, MD

CONTACT

+573112517471; norton.perez@hotmail.com

Emma I Rodriguez Darabos, MSc

CONTACT

3112517538; emmaisa1@hotmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: September 28, 2025
• First Posted: October 6, 2025
• Study Start: January 1, 2026
• Primary Completion (Estimated): December 1, 2028
• Study Completion (Estimated): December 1, 2028
• Last Updated: November 21, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

CO (1)