NCT07205445

Brief Summary

Tensi+ (Stimuli Technology, Boulogne Billancourt, France) is a newly released, medical transcutaneous-posterior tibial nerve stimulation (TC-pTNS) device marketed for overactive bladder (OAB) management. Preliminary studies have shown a favorable safety and efficacy profile. The goal of the present registry is to collect data among an important number of patients to assess the efficacy, safety and potential predictive factors of success in a current clinical setting over a total period of 1 year.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
18mo left

Started Feb 2025

Typical duration for all trials

Geographic Reach
3 countries

17 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress46%
Feb 2025Oct 2027

Study Start

First participant enrolled

February 27, 2025

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

September 16, 2025

Completed
17 days until next milestone

First Posted

Study publicly available on registry

October 3, 2025

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2027

Last Updated

October 3, 2025

Status Verified

September 1, 2025

Enrollment Period

2.6 years

First QC Date

September 16, 2025

Last Update Submit

September 30, 2025

Conditions

Keywords

UrologyTENSOveractive bladder

Outcome Measures

Primary Outcomes (1)

  • Subjective improvement

    The Patient Global Impression of Improvement (PGI-I) uses a 7-point scale, where post-treatment condition is rated as follows: 1. = Very much better 2. = Much better 3. = A little better 4. = No change 5. = A little worse 6. = Much worse 7. = Very much worse. For analysis, patients with a PGI-I score of 1, 2, or 3 are typically considered responders, reflecting meaningful improvement.

    3 and 12 months

Secondary Outcomes (3)

  • Patient-reported Outcomes Measures (PROMs)

    0; 3 and 12 months

  • Patient-reported Outcomes Measures (PROMs)

    0; 3 and 12 months

  • Quality of life measures

    0; 3 and 12 months

Other Outcomes (6)

  • Patient-reported Outcomes Measures (PROMs)

    0; 3 and 12 months

  • Evaluation of voiding frequency

    0; 3 and 12 months

  • Evaluation of urgency

    0; 3 and 12 months

  • +3 more other outcomes

Interventions

Tensi+DEVICE

Tensi+ (Stimuli Technology, Boulogne Billancourt, France) is a newly released, medical transcutaneous-posterior tibial nerve stimulation (TC-pTNS) device marketed for overactive bladder (OAB) management.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Age ≥ 18 years Overactive bladder symptoms

You may qualify if:

  • Age ≥ 18 years
  • Patients suffering from idiopathic or neurological overactive bladder

You may not qualify if:

  • Patients with pacemaker, defibrillator, or any other electronic implant;
  • Patients with metal implant near the stimulation area;
  • Pregnant women;
  • People suffering from ankle joint problems, swollen ankles or a dermatological condition or damaged skin in the area where the electrodes are to be placed;
  • Patient with cognitive impairment;
  • Inability to complete a voiding diary;
  • No social security cover (for applicable countries).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (17)

HFME - Hospices Civils de Lyon

Bron, 69500, France

RECRUITING

CHU de Rennes

Rennes, 35033, France

RECRUITING

CHU de Rennes

Rennes, 35033, France

RECRUITING

CHU de Rouen - Hôpital Charles Nicolle

Rouen, 76031, France

RECRUITING

Nuova Villa Esther

Avellino, 83100, Italy

NOT YET RECRUITING

Azienda Ospedaliero-Universitaria Careggi

Florence, 50139, Italy

NOT YET RECRUITING

Hesperia Hospital

Modena, 41125, Italy

NOT YET RECRUITING

Santa Maria la Gruccia Hospital

Montevarchi, 52025, Italy

NOT YET RECRUITING

Policlinico Tor Vergata

Roma, 00133, Italy

NOT YET RECRUITING

Casa di Cura Villa Stuart

Roma, 00135, Italy

NOT YET RECRUITING

Villa Salaria Hospital

Roma, 00139, Italy

NOT YET RECRUITING

Azienda Ospedaliero Universitaria Sant'Andrea

Roma, 00189, Italy

NOT YET RECRUITING

Azienda Ospedaliero Universitaria Sant'Andrea

Roma, 00189, Italy

NOT YET RECRUITING

Clinica Nuova Villa Claudia

Roma, 00191, Italy

NOT YET RECRUITING

Bristol Urological Institute

Bristol, BS10 5NB, United Kingdom

NOT YET RECRUITING

Addenbrooke's Hospital, Cambridge University Hospital Trust

Cambridge, CB22 0QQ, United Kingdom

NOT YET RECRUITING

University College Hospital London

London, NW1 2BU, United Kingdom

NOT YET RECRUITING

MeSH Terms

Conditions

Urinary Bladder, Overactive

Condition Hierarchy (Ancestors)

Urinary Bladder DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesLower Urinary Tract SymptomsUrological ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Year
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 16, 2025

First Posted

October 3, 2025

Study Start

February 27, 2025

Primary Completion (Estimated)

October 1, 2027

Study Completion (Estimated)

October 1, 2027

Last Updated

October 3, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Locations