NCT07202169

Brief Summary

The purpose of this study is to study the law of intramural diffusion of low rectal cancer in different stages, and to explore the relationship between intramural diffusion of low rectal cancer and the distal resection margin during operation, so as to provide theoretical basis for clinicians to formulate accurate and individualized treatment plans, and help improve the prognosis and quality of life of patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
106

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Dec 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2024

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2025

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2025

Completed
22 days until next milestone

First Submitted

Initial submission to the registry

September 23, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

October 1, 2025

Completed
Last Updated

October 1, 2025

Status Verified

September 1, 2025

Enrollment Period

6 months

First QC Date

September 23, 2025

Last Update Submit

September 23, 2025

Conditions

Rectal Cancer PatientsRectal Cancer Stage

Outcome Measures

Primary Outcomes (1)

  • the distance of intramural spread

    2023.01-2024.12

Study Arms (4)

Patients with T1 ultra-low rectal cancer

Patients with T2 ultra-low rectal cancer

Patients with T3 ultra-low rectal cancer

Patients with T4 ultra-low rectal cancer

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with ultra-low rectal cancer

You may qualify if:

  • Patients aged 18-75 years old
  • Pathology suggestive of moderately to highly differentiated rectal adenocarcinoma
  • Tumor lower margin ≤ 5 cm from the anal verge
  • No distant metastasis such as lung, liver and other organs

You may not qualify if:

  • Preoperative patients with severe underlying diseases (such as severe liver and kidney function, cardiopulmonary function, coagulation dysfunction, etc.)
  • Patients with malignant tumors in other parts of the body

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The First Affiliated Hospital of Whenzhou Medical University

Wenzhou, Zhejiang, China

Location

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 23, 2025

First Posted

October 1, 2025

Study Start

December 1, 2024

Primary Completion

June 1, 2025

Study Completion

September 1, 2025

Last Updated

October 1, 2025

Record last verified: 2025-09

Locations

CN(1)