NCT07201571

Brief Summary

This retrospective cohort study was conducted using the Registry for Thoracic Cancer Surgery at Samsung Medical Center (Seoul, South Korea), which has included all patients who underwent thoracic surgery

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,131

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 1994

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 6, 1994

Completed
30.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2025

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

September 23, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

October 1, 2025

Completed
Last Updated

October 1, 2025

Status Verified

September 1, 2025

Enrollment Period

30.8 years

First QC Date

September 23, 2025

Last Update Submit

September 23, 2025

Conditions

Oesophageal Squamous Cell Carcinoma

Keywords

Oesophageal Squamous Cell CarcinomaEsophagectomy

Outcome Measures

Primary Outcomes (1)

  • Postoperative complications

    Complications related to fluid imbalance and portal hypertension, such as ascites, pleural effusion, and chyle leak; complications associated with impaired renal or hematologic function, including acute kidney injury, bleeding, and graft failure; and complications reflecting immune dysfunction and infection susceptibility, including pneumonia and empyema. Complications associated with impaired tissue healing, such as anastomotic leakage, were also analyzed. Liver failure and acute respiratory distress syndrome were considered separately. All complications were defined according to the Esophageal Complications Consensus Group, and their severity was assessed according to the Clavien-Dindo classification.

    within 90 days after surgery

Secondary Outcomes (1)

  • Overall survival

    10 years after surgery

Study Arms (1)

Patients who underwent curative surgery for esophageal cancer

Patients who underwent curative surgery for esophageal cancer

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who underwent curative surgery for esophageal cancer

You may qualify if:

  • Patients who underwent curative surgery for esophageal cancer

You may not qualify if:

  • cervical esophageal cancer
  • gastroesophageal junction cancer
  • histology other than squamous cell carcinoma
  • patients with Child-Pugh class B or C liver cirrhosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Esophageal Squamous Cell Carcinoma

Condition Hierarchy (Ancestors)

Carcinoma, Squamous CellCarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsNeoplasms, Squamous CellEsophageal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteHead and Neck NeoplasmsDigestive System DiseasesEsophageal DiseasesGastrointestinal Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Samsung Medical Center

Study Record Dates

First Submitted

September 23, 2025

First Posted

October 1, 2025

Study Start

November 6, 1994

Primary Completion

August 31, 2025

Study Completion

August 31, 2025

Last Updated

October 1, 2025

Record last verified: 2025-09