Prevalence of Postpartum Depression Among Patients of the CHUM GARE Clinic

NCT07200323 | Recruiting

• 1 other identifier: 2026-13020
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Postpartum depression (PPD) is a frequent complication of the postnatal period but remains underdetected in routine clinical practice. This prospective clinical study, conducted at the high-risk pregnancy clinic of the CHUM, aims to estimate the prevalence of PPD among patients seen in postpartum follow-up. It also assesses the feasibility of implementing a standardized screening protocol that combines the administration of the Edinburgh Postnatal Depression Scale (EPDS) with a clinical decision-support algorithm to guide appropriate medical follow-up. The study also seeks to explore clinical characteristics associated with higher EPDS scores.

Conditions

Post-partum Depression; Maternal Health; Mental Health Issue

Outcome Measures

Primary Outcomes (1)

• Prevalence of postpartum depression in the study population

  Proportion of patients with an EPDS score ≥13 at the 4 to 8-week postpartum visit. The Edimburgh Postnatal Depression Scale (EPDS) is a validated 10-item questionnaire designed to identify symptoms of depression in postnatal mothers. Each question asks about feelings and experiences over the past seven days, covering various emotional and psychological aspects related to perinatal mood. For each question, there are four possible responses, scored from 0 to 3, with higher numbers indicating more severe symptoms. The total EPDS score indicates the severity of potential depressive symptoms: a score of 13 or above often suggests a high risk of developing a depressive disorder.

  Baseline EPDS score (Day 0)

Secondary Outcomes (4)

• Orientation to a medical or psychosocial resource based on EPDS score and decision algorithm

  Immediately after EPDS completion

• Repeat EPDS score at 2-week follow-up (for scores between 13 and 16 only)

  2 weeks after initial EPDS score

• Number of days before the first contact with referred service

  Assessed at two-week and, if needed, six-week follow-up calls

• Clinical and obstetrical factors associated with EPDS ≥13

  Chart review conducted following Day 0 visit and consent

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: Women who gave birth within the last 4 weeks to 6 months at CHUM
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients of the high-risk pregnancy clinic (GARE - Grossesse à risque élevé) of the Centre hospitalier de l'Université de Montréal (CHUM) coming in for their post-partum visit with obstetrician

You may qualify if:

• Patients aged 18 years or more
• Patient who gave birth within the last 4 weeks to 6 months
• Ability to understand French or English and complete the EPDS questionnaire
• Physically present at their post-partum visit at the clinic

You may not qualify if:

• Inability to comprehend and/or complete the EPDS
• Declines participation or does not provide informed consent

Sponsors & Collaborators

• Centre hospitalier de l'Université de Montréal (CHUM): lead

Study Sites (1)

Centre Hospitalier de l'Université de Montréal

Montreal, Quebec, H2X 3E4, Canada

RECRUITING

MeSH Terms

Conditions

Depression, Postpartum

Condition Hierarchy (Ancestors)

Puerperal Disorders; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Depressive Disorder; Mood Disorders; Mental Disorders

Study Officials

• Anne Lavoie, MD

  CHUM

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Anne Lavoie, MD

CONTACT

514-890-8000; anne.lavoie.med@ssss.gouv.qc.ca

Julie Desroches, PhD

CONTACT

514-890-8000; anesthesie.recherche.chum@ssss.gouv.qc.ca

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 15, 2025
• First Posted: October 1, 2025
• Study Start: October 20, 2025
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): January 1, 2027
• Last Updated: February 23, 2026

Record last verified: 2026-02

Locations

CA (1)