Conversational AI Platform for Early Pregnancy Care City-wide Recruitment: A Feasibility Study

NCT07197892 | Recruiting

• 1 other identifier: 859274
• Study Type: interventional
• Target: 2,637
• Locations: 1 country
• Sites: 1

Brief Summary

This study seeks to determine pregnant patients in the Philadelphia area can be recruited to a conversational AI texting platform. The trial will be considered feasible if recruitment goals are met in proportion to delivery volume at the hospital.

Conditions

Early Pregnancy

Keywords

Early pregnancy loss; Miscarriage; Prenatal care; Abortion

Outcome Measures

Primary Outcomes (1)

• Feasibility of citywide recruitment of pregnant patients in Philadelphia.

  Proportion of pregnant patients in Philadelphia who sign up to use CIRCA texting platform

  12 months

Secondary Outcomes (4)

• Platform engagement

  Between platform enrollment up until 12 weeks, 6 days gestation

• Platform acceptability

  To be completed at 1 week of use and at final study survey (up to 12 weeks 6 days gestation)

• Birth outcome

  From platform enrollment up until the event of a live birth or other pregnancy outcome.

• Emergency Department Utilization

  From platform enrollment until 12 weeks, 6 days gestation.

Study Arms (1)

CIRCA Texting Platform

EXPERIMENTAL

CIRCA is a two-way texting platform that uses artificial intelligence to match patient texts to clinician-vetted responses and send educational content.

Other: CIRCA Texting Platform

Interventions

CIRCA Texting Platform OTHER

Two-way texting platform that uses artificial intelligence to match patient texts to clinician-vetted responses and send educational content

CIRCA Texting Platform

Eligibility Criteria

• Age: 15 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Willing and able to provide informed consent
• Access to a working mobile phone
• Ability to read English
• Pregnant with a gestational age less than 12 weeks, 6 days by last menstrual period or by ultrasound, or per patient self-report

Sponsors & Collaborators

• University of Pennsylvania: lead

Study Sites (1)

Penn Medicine

Philadelphia, Pennsylvania, 19104, United States

RECRUITING

MeSH Terms

Conditions

Abortion, Spontaneous

Condition Hierarchy (Ancestors)

Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases

Study Officials

• Alice Abernathy

  University of Pennsylvania

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Arden McAllister, MPH

CONTACT

267-785-8044; arden.mcallister@pennmedicine.upenn.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 26, 2025
• First Posted: September 30, 2025
• Study Start: April 6, 2026
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): September 1, 2027
• Last Updated: April 23, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)