Effect of Dose Variations of High-Power Laser Therapy on Patients With Nonspecific Cervical Pain

NCT07196800 | Recruiting

• 1 other identifier: physio 2 2025
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Nonspecific neck pain, defined as pain without a specific underlying pathology, is a common musculoskeletal disorder that affects a significant proportion of the global population. Neck pain often results in considerable discomfort and functional limitations, impacting individuals' quality of life and ability to perform daily tasks. Estimates suggest that up to 30% of adults experience neck pain annually. The condition ranks among the top causes of disability worldwide, contributing to substantial personal and societal burdens, including lost work productivity and increased healthcare costs.

Conditions

Neck Pain

Outcome Measures

Primary Outcomes (2)

• Pain assessment

  where participants will rate their pain on a scale from 0 (no pain) to 10 (worst pain imaginable).

  4 weeks

• Cervical Range of Motion (ROM):

  ROM will be measured using an OB goniometer in three planes

  4 weeks

Study Arms (2)

lower dose laser therapy

ACTIVE COMPARATOR

Radiation: High intensity laser therapy (low dose) combined with conventional physiotherapy program

higher dose laser therapy

EXPERIMENTAL

Procedure: High intensity laser therapy (High dose) combined with conventional physiotherapy program

Interventions

High intensity laser therapy (low dose) combined with conventional physiotherapy program RADIATION

840 joules delivered during each session combined with conventional physiotherapy program Participants

lower dose laser therapy

High intensity laser therapy (High dose) combined with conventional physiotherapy program PROCEDURE

2632 joules delivered during each session combined with conventional physiotherapy program

higher dose laser therapy

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• unilateral or bilateral CNP
• Experiencing moderate to severe neck pain, defined as a Visual Analog
• Scale (VAS) score of ≥4.
• Cervical Range of Motion (ROM) Limitation: Documented restriction in cervical ROM compared to normal values for age and gender, to ensure the condition's impact on functional mobility
• Patients agreed not to take any medication(anti-inflammatories, analgesics, or muscle relaxants) throughout the course of the study or receive any type of treatment for neck pain

You may not qualify if:

• Previous Cervical Surgery: Patients with a history of cervical spine surgery will be excluded to eliminate potential influences from post-surgical changes on the outcomes
• Diagnosed with cervical disc prolapse as confirmed by clinical evaluation and imaging studies (MRI or CT scans).
• History of malignancy in the cervical region or other serious medical conditions.
• Severe comorbidities that may affect treatment outcomes (e.g., uncontrolled diabetes, cardiovascular diseases).
• Pregnancy or lactation.

Sponsors & Collaborators

• Deraya University: lead

Study Sites (1)

Deraya university physiotherapy clinic

Minya, 05673, Egypt

RECRUITING

MeSH Terms

Conditions

Neck Pain

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 20, 2025
• First Posted: September 29, 2025
• Study Start: March 10, 2025
• Primary Completion: November 10, 2025
• Study Completion: December 1, 2025
• Last Updated: September 29, 2025

Record last verified: 2025-09

Locations

EG (1)