Prevalence of Periodontitis in Egyptian Multiple Sclerosis Patients.

NCT07195110 | Completed

• 1 other identifier: PER4-1-2
• Study Type: observational
• Target: 293
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to explore the association between multiple sclerosis and periodontal disease in a sample of Egyptian population The main question it aims to answer is: • Is there an association between MS and periodontal disease Participants already diagnosed with multiple sclerosis. A conventional oral examination will be held on a dental unit, filling charts and patients' acceptance to participate in the survey.

Conditions

Multiple Sclerosis (MS); Periodontal Diseases

Outcome Measures

Primary Outcomes (1)

• Prevalence of periodontal disease as assessed by clinical periodontal parameters ( clinical attachment loss )within the study population.

  CAL will be measured as the distance from the cementoenamel junction (CEJ) to the base of the periodontal pocket using a periodontal probe at six sites per tooth. Mean CAL will be calculated for each participant to assess periodontal tissue destruction.

  Baseline

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

MS patients to be recruited and selected from sheikh Zayed Al-Nahayan Hospital

You may qualify if:

• Patients diagnosed with MS
• Adult patients ≥ 18 years old.
• Patients providing an informed consent

You may not qualify if:

• Periodontal therapy within the last 3 months.
• Having surgical therapy or undergoing orthodontic treatment
• Smokers
• Pregnant females
• Patients with systemic condition know to impact the periodontal condition other than MS (eg. Diabetes Mellitus)
• Patients having more than 5 lost teeth

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Hospital

Cairo, 0000, Egypt

Location

MeSH Terms

Conditions

Multiple Sclerosis; Periodontal Diseases

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Mouth Diseases; Stomatognathic Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: September 17, 2025
• First Posted: September 26, 2025
• Study Start: September 18, 2025
• Primary Completion: February 1, 2026
• Study Completion: March 16, 2026
• Last Updated: March 18, 2026

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)