This Project is a Three-arm RCT Evaluating Two, Single-session Behavioral Interventions for Adults With Chronic Musculoskeletal Pain (CMP) -- 1) Brief Mindfulness-Oriented Recovery Enhancement (B-MORE) vs. Empowered Relief (ER) -- Relative to the Traditional 8-week Version of MORE.

NCT07193095 | Recruiting

• 1 other identifier: 00006036
• Study Type: interventional
• Target: 39
• Locations: 1 country
• Sites: 1

Brief Summary

Researchers at Florida State University are investigating how the length of treatment influences outcomes for individuals with chronic musculoskeletal pain. The goal is to identify the most effective balance between treatment duration and pain relief. There are three treatment conditions in this study: two different brief pain management trainings and one standard-length training. Participants will be randomized to either of the brief trainings, attending a single, 2-hour, online training session, in which a trained facilitator will teach pain management techniques that are backed by research. If randomized to receive the standard-length training, participants will attend eight, 2-hour, online training session over eight weeks, in which a trained facilitator will also teach research-backed pain management techniques. Short surveys will be required at seven different time points: before starting treatment, immediately after the pain-management training, and then 2, 6, 12, 24, and 36 weeks after the training.

Conditions

Chronic Musculoskeletal Pain

Keywords

Chronic pain; Brief intervention; Remote

Outcome Measures

Primary Outcomes (2)

• Recruitment Feasibility

  Recruitment feasibility will be assessed via total enrollment and randomization numbers within the first 6 months of the study. Study team projects that it will be feasible to recruit and randomize 30 adults with CMP within 6 months.

  6 months

• Treatment Adherence & Acceptability

  Adherence (percentage of total treatment time attended) will be better for the single-session interventions, but all three conditions will be rated as highly acceptable (as measured by the Theoretical Framework of Acceptability; TFA).

  From baseline to 9-month follow-up

Secondary Outcomes (2)

• PROMIS - Pain Intensity

  From baseline to 9-month follow-up

• PROMIS - Pain Interference

  From baseline to 9-month follow-up

Other Outcomes (9)

• PROMIS - Depression

  From baseline to 9-month follow-up

• PROMIS - Anxiety

  From baseline to 9-month follow-up

• PROMIS - Sleep Disturbance

  From baseline to 9-month follow-up

Study Arms (3)

Brief Mindfulness Oriented Recovery Enhancement (B-MORE)

EXPERIMENTAL

B-MORE is a 2-hour, single session adaptation of the traditional MORE program.

Behavioral: Brief Mindfulness Oriented Recovery Enhancement

Empowered Relief (ER)

EXPERIMENTAL

ER is an evidence-based 2-hour single session intervention for chronic pain

Behavioral: Empowered Relief

Mindfulness Oriented Recovery Enhancement (MORE)

EXPERIMENTAL

MORE is an 8-week evidence-based treatment for chronic pain.

Behavioral: Mindfulness Oriented Recovery Enhancement

Interventions

Brief Mindfulness Oriented Recovery Enhancement BEHAVIORAL

B-MORE is a 2-hour, single session adaptation of the traditional MORE program.

Brief Mindfulness Oriented Recovery Enhancement (B-MORE)

Empowered Relief BEHAVIORAL

ER is an evidence-based 2-hour single session intervention for chronic pain.

Empowered Relief (ER)

Mindfulness Oriented Recovery Enhancement BEHAVIORAL

MORE is an 8-week evidence-based treatment for chronic pain.

Mindfulness Oriented Recovery Enhancement (MORE)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• (1) having a chronic musculoskeletal pain condition, (2) average pain of ≥ 3 in the previous week, (3) willingness to engage with study assessments and interventions, (4) understanding English instructions fluently, and (5) being 18 and above.

You may not qualify if:

• (1) unable to consent because of physical or mental incapacity, (2) have previous, formal mindfulness training (e.g., MBSR) or previously receiving Empowered Relief, (3) have pain from a current cancer diagnosis or cancer-related treatment, (4) unstable illness that may interfere with treatment, (5) had surgery within the previous three months, and (6) had pain relieving injections, such as cortisone or hyaluronate, within the previous three months.

Sponsors & Collaborators

• Florida State University: lead

Study Sites (1)

Research Building B

Tallahassee, Florida, 32310, United States

RECRUITING

MeSH Terms

Conditions

Chronic Pain

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Adam Hanley, PhD

CONTACT

850-270-7844; adam.hanley@fsu.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: September 17, 2025
• First Posted: September 25, 2025
• Study Start: August 14, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: September 25, 2025

Record last verified: 2025-09

Locations

US (1)