NCT07189611

Brief Summary

This study aims to design, implement, and evaluate a blended online and offline teaching model for Internal Medicine Nursing, integrating generative artificial intelligence (GAI), a virtual simulation platform, card-based exercises, and scenario simulation. The objective is to address key limitations of traditional teaching, including low student engagement, insufficient cultivation of clinical thinking, limited personalized learning, and a disconnect between theory and practice. A mixed-methods approach will be used. All undergraduate nursing students from the 2024 cohort at Changsha Medical University will be enrolled via convenience sampling as the experimental group to receive the new blended model. The 2023 cohort will serve as the control group, receiving traditional teaching. Quantitative data (course grades, satisfaction questionnaires) and qualitative data (semi-structured interviews) will be collected to comprehensively evaluate the model's effectiveness. Expected outcomes include improved student mastery of theoretical knowledge, enhanced practical skills and clinical thinking, increased learning interest, and higher teaching satisfaction. The study intends to provide a replicable, scalable innovative solution for nursing education reform, ultimately contributing to the training of high-quality applied nursing talents. Key problems addressed: Overcoming single-method teaching and poor interaction through GAI and gamification. Enhancing clinical thinking and decision-making via dynamic GAI cases and card-based exercises. Providing personalized learning paths and instant feedback using GAI technology. Bridging the theory-practice gap with high-fidelity virtual and scenario simulations. Implementing a multi-dimensional evaluation system beyond final exams to assess comprehensive student abilities.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
600

participants targeted

Target at P75+ for not_applicable

Timeline
25mo left

Started Jan 2026

Typical duration for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress14%
Jan 2026Jun 2028

First Submitted

Initial submission to the registry

August 27, 2025

Completed
28 days until next milestone

First Posted

Study publicly available on registry

September 24, 2025

Completed
3 months until next milestone

Study Start

First participant enrolled

January 1, 2026

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2028

Expected
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2028

Last Updated

September 24, 2025

Status Verified

September 1, 2025

Enrollment Period

2 years

First QC Date

August 27, 2025

Last Update Submit

September 19, 2025

Conditions

Keywords

generative artificial intelligencepractical teachingInternal Medicine Nursingblended online and offline teaching model

Outcome Measures

Primary Outcomes (2)

  • Course Scores

    The total course score is a composite measure evaluating overall academic performance. It comprises two components: a theoretical knowledge score (assessed via a closed-book examination, scored out of 100 points) and a practical skill assessment score (evaluated through case analysis, emergency drill simulations, virtual simulation performance, and online course participation, each contributing 20% to the practical score, which is also scaled to 100 points). The final total course score is calculated by weighting the theoretical score at 60% and the practical score at 40%, resulting in a composite value out of 100.

    At the end of the 6-month course.

  • Teaching Satisfaction Score

    Teaching satisfaction will be measured using a validated evaluation questionnaire developed based on a review of relevant literature, research group discussions, and consultation with nursing education experts. The questionnaire produces a quantitative satisfaction score.

    At the end of the 6-month course.

Secondary Outcomes (2)

  • Online and Offline Teaching Effect Evaluation

    At the end of the 6-month course.

  • Qualitative Interviews

    Within one month after completion of the 6-month course.

Study Arms (1)

Experimental group

EXPERIMENTAL

(2) Experimental Group Teaching Implementation Process: a blended online and offline teaching model based on generative artificial intelligence ① Pre-class Preview: Students join the teaching QQ group and Learning Terminal group before class, complete the learning of online resources on the Learning Terminal platform, and perform virtual simulation experiments. ② In-class Implementation: Teaching is conducted in small groups. Each class is divided into 4 small groups, with 4-5 students forming one team for card-based desktop exercise teaching and scenario simulation teaching, each session lasting 2 class hours.③ Post-class Review: Students use generative AI (Deepseek) for knowledge consolidation and to access new technologies and research advancements related to the course content.

Behavioral: A blended online and offline teaching model for internal medicine nursing practice based on generative artificial intelligence

Interventions

This study will employ a convergent mixed-methods design. Participants will be convenience-sampled undergraduate nursing students from the 2024 cohort (intervention group) and the 2023 cohort (control group) at Changsha Medical University. The intervention group will experience the new blended model, which includes: 1) Optimizing a GAI-assisted clinical case library with progressive scenarios; 2) Utilizing online resources (Learning Terminal platform, virtual simulation experiments with an AI assistant); 3) Engaging in offline interactive sessions (card-based desktop deduction games and scenario simulations). The control group will receive traditional teaching methods. Quantitative data will include course scores (theoretical knowledge and practical skills) and teaching satisfaction questionnaires. Qualitative data will be collected via semi-structured interviews to explore students' experiences deeply.

Experimental group

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Nursing major students;
  • Four-year undergraduate students.

You may not qualify if:

  • Students who drop out midway;
  • Students whose absences accumulate to exceed 30% of the total class hours.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SEQUENTIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Staff Nurse

Study Record Dates

First Submitted

August 27, 2025

First Posted

September 24, 2025

Study Start

January 1, 2026

Primary Completion (Estimated)

January 1, 2028

Study Completion (Estimated)

June 1, 2028

Last Updated

September 24, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Protection of Participant Privacy and Confidentiality: Our primary ethical obligation is to protect the privacy and confidentiality of our student participants. Informed Consent Limitations: The informed consent process for this study, approved by the institutional ethics review board, explicitly outlines how the collected data will be used (i.e., for aggregate analysis to evaluate teaching effectiveness within the confines of this research project). Nature of the Data and High Risk of Re-identification: The qualitative interview data are particularly sensitive.