NCT07184957

Brief Summary

This will be a prospectively maintained research database. The purpose is to record baseline parameters and treatment outcomes following of Cryotherapy for ablation of clinically localized prostate cancer.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
175mo left

Started May 2017

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress39%
May 2017Dec 2040

Study Start

First participant enrolled

May 1, 2017

Completed
8.4 years until next milestone

First Submitted

Initial submission to the registry

September 15, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 22, 2025

Completed
5.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2030

Expected
10 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2040

Last Updated

September 22, 2025

Status Verified

September 1, 2025

Enrollment Period

13.7 years

First QC Date

September 15, 2025

Last Update Submit

September 15, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Treatment Complications

    Up to Year 15

  • PSA-Progression Free Survival

    Length of time following cryotherapy for ablation treatment of prostate cancer that a patient lives without their prostate-specific antigen (PSA) levels rising significantly enough to indicate disease recurrence, or without dying from any cause.

    Up to Year 15

Study Arms (1)

Men with Prostate Cancer

Men who receive cryotherapy for ablation of clinically localized prostate cancer.

Eligibility Criteria

Age40 Years - 85 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Men who receive cryotherapy for ablation of clinically localized prostate cancer.

You may qualify if:

  • Evidence of focal prostate cancer confined to the prostate based on MRI imaging and prostate biopsy

You may not qualify if:

  • Men that are not diagnosed with prostate cancer.
  • Men that are diagnosed with clinically localized prostate cancer, but select other treatment options as their desired treatment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NYU Langone Health

New York, New York, 10016, United States

RECRUITING

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Study Officials

  • James Wysock, MD

    NYU Langone Health

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 15, 2025

First Posted

September 22, 2025

Study Start

May 1, 2017

Primary Completion (Estimated)

December 31, 2030

Study Completion (Estimated)

December 31, 2040

Last Updated

September 22, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will share

The de-identified participant data from the final research dataset will be shared upon reasonable request beginning 9 to 36 months after publication or as required by a condition of awards or supporting agreements, provided the requesting investigator executes a data use agreement with NYU Langone Health. This instance of data sharing will also require separate IRB review as well as review from NYU Langone's Data Sharing Strategy Board (DSSB). Requests should be directed to: James.Wysock@nyulangone.org. The protocol and statistical analysis plan will be posted on Clinicaltrials.gov only as required by federal regulation or supporting awards and agreements.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Beginning 9 months and ending 36 months following article publication or as required by a condition of awards and agreements supporting the research.
Access Criteria
The investigator who proposed to use the data will be granted access upon reasonable request. Requests should be directed to James.Wysock@nyulangone.org. To gain access, data requestors will need to sign a data access agreement. This instance of data sharing will also require separate IRB review as well as review from NYU Langone's DSSB.

Locations