Investigating Practice Patterns in Symptomatic Non-ruptured Abdominal Aortic Aneurysms (AAA) in Europe

NCT07184723 | Recruiting

• 1 other identifier: EK_24_063_VK
• Study Type: observational
• Target: 130
• Locations: 1 country
• Sites: 1

Brief Summary

Symptomatic non-ruptured abdominal aortic aneurysms (snrAAA) remain a clinical challenge due to limited evidence and heterogeneous definitions and management strategies. Unlike ruptured AAAs, snrAAA lack large-scale population-based studies, primarily due to inconsistent application of standardised medical classifications (e.g., ICD-10) and international variability in definitions, diagnostic approaches, and treatment protocols. Optimal diagnostic pathways, preoperative risk assessments, and treatment strategies remain poorly defined, with minimal guidance from existing guidelines. This study aims to conduct a multinational cross-sectional online survey with optional retrospective validation to assess current opinions on an institutional scale regarding the definition and management of patients with snrAAA in Europe. All European vascular centres offering elective and emergency AAA repair are eligible to participate. Multiple survey entries from the same institution are not allowed. Centres are also invited to participate in a retrospective observational validation, reporting diagnostic and therapeutic details of their last five snrAAA cases.

Conditions

Symptomatic Non-ruptured Abdominal Aortic Aneurysms

Keywords

abdominal aortic aneurysm; symptomatic non-ruptured; vascular surgery; Europe

Outcome Measures

Primary Outcomes (1)

• Number of participants that define non-ruptured symptomatic AAA on clinical symptoms alone assessed by the snrAAA Questionaire

  The objective of this study is to provide insights into current practice strategies in the definition, diagnosis, preoperative optimization, and surgical care of patients with non-ruptured symptomatic AAA in Europe. Primary outcome measures will be count and proportion.

  From August 2024 to June 2026

Secondary Outcomes (1)

• Number of participants where the stated practices align with actual treatment patterns assessed by the snrAAA Questionaire and electronic Case Report Form

  From August 2024 to June 2026

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

European vascular centres offering elective and emergency AAA repair

You may qualify if:

• \- Last 5 patients (aged \>18 years) treated at a participating centre for symptomatic non-ruptured AAA (or the last patients in the preceding 5 years if they have treated less than 5 patients in 5 years)

You may not qualify if:

• None

Sponsors & Collaborators

• Wilhelminenspital Vienna: lead

Study Sites (1)

Department of Vascular and Endovascular Surgery, Clinic Ottakring

Vienna, Vienna, 1160, Austria

RECRUITING

MeSH Terms

Conditions

Aortic Aneurysm, Abdominal

Condition Hierarchy (Ancestors)

Aortic Aneurysm; Aneurysm; Vascular Diseases; Cardiovascular Diseases; Aortic Diseases

Central Study Contacts

Maria Elisabeth Leinweber, MD

CONTACT

+43 1 49150 4110; maria-elisabeth.leinweber@gesundheitsverbund.at

Amun Georg Hofmann, MD

CONTACT

+43 1 49150 4110; amungeorg.hofmann@gesundheitsverbund.at

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of Department

Study Record Dates

• First Submitted: July 9, 2025
• First Posted: September 22, 2025
• Study Start: August 1, 2024
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: September 22, 2025

Record last verified: 2025-06

Locations

AU (1)