The Effectiveness of Lower Extremity Strength Training

NCT07183969 | Completed DMC

• 1 other identifier: CShih
• Study Type: interventional
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

The increase in chronic schizophrenia patients with sarcopenia is currently an important healthcare issue in Taiwan and requires enhanced prevention and progress. Therefore, the purpose of this study was to understand the prevalence of sarcopenia in patients with chronic schizophrenia and to explore the effect of lower limb strength training on the physical functional performance of patients with chronic schizophrenia and sarcopenia. This study adopted a quasi-experimental design method, and the research process was divided into two stages. In the first stage, the SARC-CalF questionnaire was used to initially screen suspected chronic schizophrenia patients in a psychiatric hospital in central Taiwan. For sarcopenia cases, the skeletal muscle mass index (Skeletal Muscle Mass index) of suspected sarcopenia cases is further compared with the body composition analyzer (Inboby) to confirm the diagnosis of sarcopenia. Statistical analysis of the prevalence of sarcopenia in patients with chronic schizophrenia. In the second phase of the study, 4 chronic disease areas (two chronic disease areas for men and women) were randomly divided into experimental groups and control groups. The experimental group received a 16-week lower limb muscle strength training program, while the control group received routine care. The two groups conducted one pre-test and two post-tests, and the measurement content included physical function performance (Short Physical Performance Battery (SPPB), sarcopenia quality of life (SarQoL), and fall incidence). It is expected that the development of a set of non-pharmacological care measures will help patients in chronic psychiatric wards to become independent and slow down the progression of sarcopenia.

Conditions

Patients With Chronic Schizophrenia

Keywords

Lower extremity strength training

Outcome Measures

Primary Outcomes (3)

• Short Physical Performance Battery (SPPB)

  Chair Stand Test' Chair Stand Test、Balance tests、 Gait speed test

  baseline、8weeks、16weeks

• The Sarcopenia Quality of Life Questionnaire (SarQoL-TW)

  Chinese version of the Taiwan version

  baseline、8weeks、16weeks

• fall incidence

  medical records

  baseline、8weeks、16weeks

Study Arms (2)

experimental groups

EXPERIMENTAL

16-week lower limb muscle strength training program

Other: lower limb muscle strength training program

control groups

NO INTERVENTION

received routine care

Interventions

lower limb muscle strength training program OTHER

Each plyometric training session consists of warm-up stretching, lower limb plyometrics, and gentle stretching. Warm-up stretching, there are 6 movements, push the window, pull the rope, hands up, stretch from side to side, lift one foot and open and close both feet. Do 10 repetitions of each movement, 2 rounds, and keep breathing normally for a few repetitions. Lower Extremity Plyometrics: 3 rounds of 6 plyometrics with 1 minute of recovery time between each round. The six lower body plyometrics exercises are performed by gradually increasing the load in a manner that increases the number of seconds the exercise is held. Gentle Stretching: Continuous training of muscles makes them tense, stretching can lengthen muscle fibers, increase muscle elasticity, and improve blood circulation to eliminate post-training fatigue (H.K. Chen, 2022). Perform each gentle stretching movement left and right once, hold for 30 seconds each time, and keep breathing normally (no shutting up of breath).

experimental groups

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• (1) Suitable for participation in this study as assessed by the attending physician.
• (2) After explaining the purpose of the study and the study process, family members and study subjects were asked to agree to participate in the study and to complete the consent form for signature.

You may not qualify if:

• (1) Those who are unable to walk unaided.
• (2) Severe structural disability that prevents the performance of lower extremity training.
• (3) Those with severe psychiatric symptoms that prevent them from concentrating and following instructions.
• (4)Participation in a lower extremity muscle training program or intervention within one year.

Sponsors & Collaborators

• National Taipei University of Nursing and Health Sciences: lead

Study Sites (1)

Tsaotun Psychiatric Center,MOHW

Tsaotun, Nanton, 542, Taiwan

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ph.D. candidate

Study Record Dates

• First Submitted: July 16, 2024
• First Posted: September 19, 2025
• Study Start: September 20, 2024
• Primary Completion: January 16, 2025
• Study Completion: January 26, 2025
• Last Updated: September 19, 2025

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)