Does Sarcopenia Influence Rotator Cuff Tear Patterns? Radiological Insights From Patients With Rotator Cuff Syndrome
1 other identifier
observational
104
1 country
1
Brief Summary
Sarcopenia is the loss of muscle mass due to aging, which consequently leads to a decline in muscle function. It is considered an independent risk factor for falls and fractures, disability, postoperative complications, and mortality. Rotator cuff tears are known to be influenced by systemic diseases such as diabetes, hypercholesterolemia, thyroid disorders, and osteoporosis. The aim of our study is to investigate whether there is a relationship between sarcopenia and rotator cuff tears, and if so, to determine the location and type of the tear.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2025
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2025
CompletedFirst Submitted
Initial submission to the registry
September 14, 2025
CompletedFirst Posted
Study publicly available on registry
September 19, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2025
CompletedNovember 26, 2025
November 1, 2025
11 months
September 14, 2025
November 19, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
STAR value
Sarcopenia will be assessed using the STAR (Sonographic Thigh Adjustment Ratio) method. In this method, gait speed, handgrip strength (measured with a dynamometer), and the chair stand test will first be conducted. For gait speed, a 6-meter walking track will be used, and patients will be instructed to walk at their normal pace. The time will be recorded with a stopwatch, and each patient will perform the test three times, with the average recorded in meters per second (m/s). Subsequently, anterior thigh muscle thickness will be measured using ultrasonography. Based on this comprehensive evaluation, patients will be categorized as non-sarcopenic, pre-sarcopenic, or sarcopenic.
Baseline
Secondary Outcomes (1)
Radiologic evaluation of shoulder MRI
Baseline
Study Arms (2)
Patients with rotator cuff tear
Patients with parsiyel or full thickness rotator cuff tear in supraspinatus tendon
Patients without rotator cuff tear
Patients without tear in supraspnatus tendon
Interventions
A detailed evaluation of shoulder MRI scans will be conducted. The presence and severity of supraspinatus tendon tears, as well as the presence of muscle atrophy (assessed using the tangent sign), will be recorded. In addition, tears in other rotator cuff tendons, signs of tendinitis, and any other pathological findings will also be documented.
Eligibility Criteria
The study's target population will be patients aged 40 to 75 who have experienced shoulder pain for longer than three months and who have been physically evaluated and found to have rotator cuff syndrome.
You may qualify if:
- Patients with rotator cuff syndrome
- Aged between 40 and 75 years
You may not qualify if:
- History of previous shoulder surgery
- Presence of shoulder pathology other than rotator cuff syndrome
- History of surgical intervention involving the hip or thigh region
- Being wheelchair-bound or bedridden
- Presence of an oncologic disease
- Diagnosis of any neurological disorder
- Presence of cognitive impairment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Health Science University Haydarpaşa Numune Research and Training Hospital
Istanbul, Üsküdar, 34668, Turkey (Türkiye)
Related Publications (5)
Atala NA, Bongiovanni SL, Galich AM, Bruchmann MG, Rossi LA, Tanoira I, Ranalletta M. Is sarcopenia a risk factor for rotator cuff tears? J Shoulder Elbow Surg. 2021 Aug;30(8):1851-1855. doi: 10.1016/j.jse.2020.10.001. Epub 2020 Nov 4.
PMID: 33157241RESULTChung SW, Yoon JP, Oh KS, Kim HS, Kim YG, Lee HJ, Jeong WJ, Kim DH, Lee JS, Yoon JW. Rotator cuff tear and sarcopenia: are these related? J Shoulder Elbow Surg. 2016 Sep;25(9):e249-55. doi: 10.1016/j.jse.2016.02.008. Epub 2016 Apr 12.
PMID: 27083579RESULTHan DS, Wu WT, Hsu PC, Chang HC, Huang KC, Chang KV. Sarcopenia Is Associated With Increased Risks of Rotator Cuff Tendon Diseases Among Community-Dwelling Elders: A Cross-Sectional Quantitative Ultrasound Study. Front Med (Lausanne). 2021 May 5;8:630009. doi: 10.3389/fmed.2021.630009. eCollection 2021.
PMID: 34026779RESULTKara M, Kara O, Durmus ME, Analay P, Sener FE, Citir BN, Korkmaz GO, Unlu Z, Tiftik T, Gurcay E, Mulkoglu C, Yalcinkaya B, Bagcier F, Aksakal MF, Erdogan K, Sertcelik A, Cakir B, Kaymak B, Ozcakar L. The Relationship Among Probable SARCopenia, Osteoporosis and SuprasPinatus Tendon Tears in Postmenopausal Women: The SARCOSP Study. Calcif Tissue Int. 2024 Apr;114(4):340-347. doi: 10.1007/s00223-024-01183-7. Epub 2024 Feb 12.
PMID: 38342790RESULTKim JH, Jang I, Jeong S, Shin J, Yoon S, Lee H, Lee S. Examining the Relationship Between Sarcopenia and Rotator Cuff Tears: A Retrospective Comparative Study. J Clin Med. 2025 Jan 2;14(1):220. doi: 10.3390/jcm14010220.
PMID: 39797302RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- M.D
Study Record Dates
First Submitted
September 14, 2025
First Posted
September 19, 2025
Study Start
January 1, 2025
Primary Completion
December 1, 2025
Study Completion
December 30, 2025
Last Updated
November 26, 2025
Record last verified: 2025-11