NCT07182669

Not Yet Recruiting

Blood Flow and Oxygenation in the Portal Vein in Subjects Wi...

Copenhagen University Hospital, Rigshospitalet Source

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Other study identifiers

Sponsor study identifier

VEK H-25043058

Study Type

observational

Estimated enrollment

40

Locations

1 country

Sites

1

Timeline

Study Start

October 1, 2025

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Primary Completion

October 1, 2027

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Study Completion

October 1, 2028

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Brief Summary

In this study the investigators will, with an Magnetic Resonance Imaging (MRI) method, measure the oxygen content in the portal vein, which conduct the blood from the guts to the liver. Examinations will be performed on 20 subjects with meal related abdominal pain due to severe narrowing of the vessels conduction blood to the guts,compared to 20 subjects with similar narrowing of the abdominal vessels, but without meal related pain. The goal of the study is to test a non-invasive, radiation free method to diagnose patients with abdominal pain due to compromized blood supply (chronic mesenteric ischemia).

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: not yet recruiting
Estimated enrollment: 40 participants
Study completion date: October 1, 2028
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

First Submitted
September 5, 2025
Actual (reported)
First Posted
September 19, 2025
Actual (reported)
Study Start
October 1, 2025
Estimated (date passed)
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
October 1, 2027
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
October 1, 2028
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated: September 19, 2025
Status Verified: September 2025
Last Update Submitted: September 16, 2025

Conditions

Chronic Mesenteric Ischemia

Keywords

chronic mesenteric ischemiafMRIMRI-TRUSTPortal oxygen concentration

Outcome Measures

Primary Outcomes (1)

flow and oxygen concentration in the portal vein
Fasting and postprandial flow and oxygen concentration in the portal vein, measured by MRI
From enrollment Through study completion, an average of 2 years

Study Arms (2)

20 subjects with mesenteric ischemia

Intake of a meal during the MRI-scan

20 subjects with stenosis of mesnteric arteries, but no postprandial pain

Intake of a meal during the MRI-scan

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Patients recruited from the participating hospital (Copenhagen University Hospital, Rigshospitalet and Copenhagen University Hospital, Hvidovre Hospital)

You may qualify if:

\- Written informed consent

Sponsors & Collaborators

Copenhagen University Hospital, Rigshospitalet
Otherlead

Study Sites (1)

Dept. of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, Rigshospitalet

Copenhagen, State, 2100 Ø, Denmark

Ulrik B. Andersen, MDCONTACT+4528944529 ulba@regionh.dk

Biospecimen

Retention: SAMPLES WITHOUT DNA

Blood samples analyzed for GIP and GLP-1

Study Officials

Ulrik B Andersen, MD, Consultant
Dept. of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Glostrup
PRINCIPAL INVESTIGATOR

Central Study Contacts

Ulrik B. Andersen, MD

CONTACT

+4528944529 ulba@regionh.dk

Bryan Haddock, Leading physician

CONTACT

+4520646534

Study Design

Study Type: observational
Observational Model: CASE CONTROL
Time Perspective: CROSS SECTIONAL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Principal investigator, MD, Consultant

Study Record Dates

First Submitted

September 5, 2025

First Posted

September 19, 2025

Study Start

October 1, 2025

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Primary Completion

NCT03586739

Evaluation of Covered Stents Versus Bare Metal Stents for Endovascular Treatment of Chronic Ischemia Mesenteric Disease.

Not ApplicableCompleted

NCT06468774

Intestinal Ischemia Biomarker in Patients With Chronic Mesenteric Ischemia

Recruiting

Male or female persons \> 18 years

Subjects with postprandial abdominal pain considered compatible with mesenteric ischemia, and severe stenosis of the SMA and eventually other mesenteric arteries, diagnosed with CT-angiography or Doppler ultrasound

OR subjects with severe stenosis of the SMA and eventually other mesenteric arteries, diagnosed with CT-angiography or Doppler ultrasound, but not postprandial pain

You may not qualify if:

\- Serious concurrent illness
BMI \> 30
Cardiac arrhythmia
Anemia with Hgb \< 7,0 mmol/l
Pregnancy or breastfeeding (urine HCG is performed on all fertile women)
Systolic blood pressure \< 90 or \> 200 mmHg
Claustrophobia
Patients who, in the judgement of the investigator, is incapable of participating
Metallic foreign objects in the body, or pacemakers

Contact the study team to confirm eligibility.

bryan.haddock@regionh.dk

October 1, 2027

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Study Completion

October 1, 2028

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated

September 19, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing: Will share
Shared Documents: CSR
Time Frame: Beginning 3 months and ending 3 years after the publication of results
Access Criteria: Forwarded by reasonably motivated request

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT07182669
Data provider: ClinicalTrials.gov
Source updated: 2025-09-19
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:26:30 UTC

Locations

DK(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Study Arms (2)

20 subjects with mesenteric ischemia

20 subjects with stenosis of mesnteric arteries, but no postprandial pain

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Biospecimen

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations